Ink Synthesis

Ink synthesis is the formulation and preparation of an ink by combining materials to achieve defined flow, stability, and functional properties. In bioengineering, it commonly produces bioinks by dispersing cells, polymers, biomolecules, or other biomaterials in a printable medium; properties such as viscosity, shear-thinning behavior, and crosslinking control how the material deposits and retains its structure. Carefully synthesized bioinks support extrusion, inkjet, or other forms of three-dimensional bioprinting while maintaining conditions compatible with living cells. These materials are important for tissue engineering, regenerative medicine, disease models, and the development of engineered tissues with controlled architecture.

Ink Synthesis - Related Videos

Research

JoVE Journal - Bioengineering
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Planar and Three-Dimensional Printing of Conductive Inks

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Cited by 58 •

2011

Planar and three-dimensional printing of conductive metallic inks is described. Our approach provides new avenues for fabricating printed electronic, optoelectronic, and biomedical devices in unusual layouts at the microscale.

Research

JoVE EoE - Breast Cancer

India Ink Inflation: A Staining Method to Visualize Tumor Nodules

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2023

This video describes india ink inflation--a staining method--to quantify tumor nodules in tumor-bearing mouse lungs. After staining, the lungs are fixed in Fekete's solution to observe tumor nodules in the lungs.

Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels

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Cited by 16 •

2013

Analysis of rodent cerebrovascular anatomy plays an important role in experimental stroke research. In this context, intravascular perfusion with colored latex has been considered as a standard tool for several years. However, this technique implies distinct technical limitations, which undermine its reproducibility. Here, we describe a simple method to visualize cerebral vessels in a reproducible manner. Injection of a mixture of two commercially available carbon black inks through the left...

Diffuse Reflectance Infrared Spectroscopic Identification of Dispersant/Particle Bonding Mechanisms in Functional Inks

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Cited by 11 •

2015

Formulation of stable, functional inks is critical to expanding the applications of additive manufacturing. In turn, knowledge of the mechanisms of dispersant/particle bonding is required for effective ink formulation. Diffuse Reflectance Fourier Transform Infrared Spectroscopy (DRIFTS) is presented as a simple, inexpensive way to gain insight into these mechanisms.

Education

JoVE Science Education - Engineering

Hydrogel Synthesis

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2023

Source: Amber N. Barron, Ashlea Patterson, and Taylor D. Sparks, Department of Materials Science and Engineering, The University of Utah, Salt Lake City, UT Hydrogels are a versatile class of cross-linked polymers produced through relatively simple procedures and with generally inexpensive materials. They can be formed from solution and involve a polymer backbone formed from monomer reagents, an initiator which makes the polymer reactive and a crosslinking species which binds the polymer chains...

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