Metabolic Rate

Metabolic rate is the amount of energy an organism uses over a given period, making it a central measure of how living systems sustain cellular activity and maintain physiological function. Cells obtain this energy by breaking down nutrients through metabolic pathways that produce ATP, while overall expenditure reflects basal maintenance, physical activity, digestion, and thermoregulation; hormones and environmental conditions can alter these processes. In biology, measuring metabolic rate helps researchers compare energy use among organisms, assess adaptations to temperature or resource availability, and investigate growth, health, exercise, and ecological energy flow.

Metabolic Rate - Related Videos

Research

JoVE Journal - Biology

Measurement of Metabolic Rate in Drosophila using Respirometry

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Cited by 49 •

2014

Metabolic disorders are among one of the most common diseases in humans. The genetically tractable model organism D. melanogaster can be used to identify novel genes that regulate metabolism. This paper describes a relatively simple method which allows studying the metabolic rate in flies by measuring their CO2 production.

Education

JoVE Core - Anatomy and Physiology

Metabolic Rate

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2024

The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities. The Basal Metabolic Rate (BMR) measures the energy expended at rest. Several factors influence the...

Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay

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Cited by 14 •

2015

This manuscript describes how herbicide metabolism rates can be effectively quantified with excised leaves from a dicot weed, thereby reducing variability and removing any possible confounding effects of herbicide uptake or translocation typically observed in whole-plant assays.

Research

JoVE Journal - Biology
Free Sample

Metabolic Profile Analysis of Zebrafish Embryos

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Cited by 42 •

2013

Zebrafish represent a powerful vertebrate model that has been under-utilised for metabolic studies. Here we describe a rapid way to measure the in vivo metabolic profile of developing zebrafish that allows the comparison of different mitochondrial function parameters between genetically or pharmacologically manipulated embryos, thereby increasing the applicability of this organism.

Metabolic Labeling

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2023

Metabolic labeling is used to probe the biochemical transformations and modifications that occur in a cell. This is accomplished by using chemical analogs that mimic the structure of natural biomolecules. Cells utilize analogs in their endogenous biochemical processes, producing compounds that are labeled. The label allows for the incorporation of detection and affinity tags, which can then be used to elucidate metabolic pathways using other biochemical analytical techniques, such as SDS-PAGE...

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