Skull Stabilization

Skull stabilization is the surgical or procedural immobilization of the head to maintain a fixed, reproducible position during neurosurgical procedures and precision imaging. It typically uses a rigid head frame or fixation device that secures the skull to an operating table or imaging platform, limiting movement and supporting accurate alignment with planned anatomical targets. In cancer research and care, stabilization helps guide brain-tumor biopsies, tumor resections, stereotactic interventions, and image-based treatment planning. By improving positional accuracy and reducing motion-related error, it supports reliable tissue sampling, safer access to lesions, and consistent assessment of treatment outcomes.

Skull Stabilization - Related Videos

Education

JoVE Core - Anatomy and Physiology

Sutures of the Skull

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2025

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures. Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

Research

JoVE Journal - Neuroscience

Isolating Immune Cells from Mouse Brain and Skull

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Cited by 1 •

2024

To investigate the immune response to brain disorders, one common approach is to analyze changes in immune cells. Here, two simple and effective protocols are provided for isolating immune cells from murine brain tissue and skull bone marrow.

Overview of the Skull

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2023

The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws. The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...

Research

JoVE Journal - Neuroscience
Free Sample

A Method to Make a Craniotomy on the Ventral Skull of Neonate Rodents

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Cited by 6 •

2014

A surgical method is described to expose the ventral skull in neonate rats. Using this approach it is possible to open a craniotomy to perform acute electrophysiology and two-photon microscopy experiments in the brainstem of anesthetized pups.

Nuclear Stability

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2020

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters. To hold positively charged protons together in the...

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