Fold-like Nanostructure

Fold-like nanostructures are nanoscale materials whose curved, pleated, or layered architectures arise from the folding or bending of molecular, polymeric, or inorganic components. Their formation is governed by nanoscale interactions, including intermolecular attraction, surface forces, and the balance between structural stiffness and flexibility, which can drive spontaneous self-assembly under controlled chemical conditions. In chemistry, these structures provide tunable surfaces, confined spaces, and altered optical, mechanical, or reactive properties. Understanding how composition and assembly conditions control folding supports the design of advanced materials for catalysis, molecular sensing, energy technologies, and other applications requiring precisely organized nanoscale structures.

Fold-like Nanostructure - Related Videos

Education

JoVE Core - Molecular Biology

Molecular Chaperones and Protein Folding

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2020

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein. The...

Protein Folding

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2020

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which is critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.Protein Structure Is Critical to Its Biological FunctionProteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...

Protein Folding

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2026

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which is critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.Protein Structure Is Critical to Its Biological FunctionProteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...

Research

JoVE Journal - Engineering

Atomically Traceable Nanostructure Fabrication

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Cited by 4 •

2015

We report a protocol for combining the atomic metrology of the Scanning Tunneling Microscope for surface patterning with selective Atomic Layer Deposition and Reactive Ion Etching. Using a robust process involving numerous atmospheric exposures and transport, 3D nanostructures with atomic metrology are fabricated.

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

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Cited by 5 •

2016

Nanoscaled sea-island surfaces composed of thermoresponsive block copolymers were fabricated by the Langmuir-Schaefer method for controlling spontaneous cell adhesion and detachment. Both the preparation of the surface and the adhesion and detachment of cells on the surface were visualized.

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