Halide Anions

Halide anions are negatively charged ions formed when halogen atoms, such as fluorine, chlorine, bromine, or iodine, gain one electron, making them fundamental participants in inorganic and organic chemistry. Their single negative charge arises from filling the halogen atom’s valence shell, and their size, polarizability, and solvation behavior vary down the group, influencing bond strength, reactivity, and solubility. In chemistry, halide anions help explain ionic compound formation, precipitation and qualitative analysis, nucleophilic substitution, and redox reactions, while their salts and complexes support laboratory identification, synthesis, materials research, and biological studies.

Halide Anions - Related Videos

Research

JoVE EoE - Viral Growth and Techniques

Anion Exchange Resin–Based Detection of Viruses from Bioaerosols

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2026

Source: Schaeffer, J. W., Chandler, et al. Detection of Viruses from Bioaerosols Using Anion Exchange Resin. J. Vis. Exp. (2018).This video demonstrates the detection of viruses from bioaerosols using an anion exchange resin. A liquid impinger containing the resin is used to capture viruses from the air. The resin is collected and treated with a virus lysis buffer containing carrier RNA. The lysate is transferred to a microcentrifuge tube for viral RNA isolation, followed by qRT-PCR to amplify...

Education

JoVE Core - Organic Chemistry

Alkyl Halides

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2023

Structural Properties Alkyl halides are halogen-substituted alkanes wherein one or more hydrogen atoms of an alkane is replaced by a halogen atom such as fluorine, chlorine, bromine, or iodine. The carbon atom in an alkyl halide is bonded to the halogen atom, which is sp3-hybridized and exhibits a tetrahedral shape. Unlike alkyl halides, compounds in which a halogen atom is bonded to an sp2 -hybridized carbon atom of a carbon-carbon double bond (C=C) are called vinyl halides. Whereas aryl...

Acid Halides to Esters: Alcoholysis

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2025

Alcoholysis is a nucleophilic acyl substitution reaction in which an alcohol functions as a nucleophile. Acid halides react with alcohol to produce esters. The mechanism proceeds in three steps: First, the alcohol acts as a nucleophile and attacks the acyl carbon to form a tetrahedral intermediate. Next, the carbonyl re-forms with the loss of a chloride ion. Lastly, the positively charged intermediate loses a proton to give an ester as the final product along with H3O+, making HCl an...

Low Pressure Vapor-assisted Solution Process for Tunable Band Gap Pinhole-free Methylammonium Lead Halide Perovskite Films

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Cited by 2 •

2017

Here, we present a protocol for the synthesis of CH3NH3I and CH3NH3Br precursors and the subsequent formation of pinhole-free, continuous CH3NH3PbI3-xBrx thin films for the application in high efficiency solar cells and other optoelectronic devices.

Mass Spectrometry: Alkyl Halide Fragmentation

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2025

Chlorine isotopes exist as 35Cl and 37Cl in a 3:1 ratio, while bromine isotopes exist as 79Br and 81Br in a 1:1 ratio. The mass spectrum of alkyl halides typically produces two distinct molecular ion peaks, the molecular ion peak, [M], and the molecular ion plus two, [M + 2] peak. The relative heights of these two peaks are proportional to the isotopic abundance ratios of the halide. For example, 2‐chloropropane and 1‐bromopropane display two peaks with relative peak heights in a 3:1 and 1:1...

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