Diagnostic Imaging
Diagnostic Imaging - Related Videos
07:12
Diagnostic Ultrasound Imaging of Mouse Diaphragm Function
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Cited by 7 •
2014
Diagnostic ultrasound imaging has proven to be effective in diagnosing various respiratory diseases in human and animal subjects. We demonstrate a comprehensive ultrasound protocol utilized by Dr. Zuo's lab to analyze diaphragm kinetics specifically in mouse models. This is also a non-invasive research technique which can provide quantitative information on mouse respiratory muscle function.
07:42
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
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Cited by 11 •
2017
We present a magnetic levitation technique coupled with automated imaging and analysis in both a smartphone-compatible device and a device with embedded imaging and processing. This is applied to measure the density distribution of cells with two demonstrated biomedical applications: sickle cell disease diagnosis and separating white and red blood cells.
08:19
Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics
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Cited by 24 •
2009
Lensfree on-chip imaging and characterization of cells is illustrated. This on-chip cell imaging approach provides a compact and cost-effective tool for medical diagnostics and high-throughput cell biology applications, making it especially suitable for resource poor settings.
10:21
Microfluidic Applications for Disposable Diagnostics
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Cited by 1 •
2008
In this interview, Dr. Klapperich discusses the fabrication of thermoplastic microfluidic devices and their application for development of new diagnostics.
21:15
Diagnostic Necropsy and Tissue Harvest
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2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Many animal experiments rely on final data collection time points that are gathered from the harvesting and testing of organs and tissues. The use of appropriate methods for the collection of organs and tissues can impact the quality of the samples and the analysis of the data that is gleaned for the testing of the tissues. The method of euthanasia of the animal can also impact the quality of...
FAQs
Each modality emphasizes a different physical signal. X-rays distinguish tissues by how strongly they attenuate radiation, ultrasound uses reflected sound waves, magnetic resonance imaging maps signals from nuclei exposed to a magnetic field, and nuclear imaging follows radiolabeled compounds. These differences determine which tissue properties or functional processes become visible and shape the information clinicians can obtain.
No single technique provides the best answer in every situation. Clinicians balance the expected diagnostic information against image resolution, acquisition time, patient condition, and potential risks, including radiation exposure. This comparison helps match the examination to the clinical question while accounting for whether the patient can tolerate the procedure and how quickly results are needed.
Image usefulness depends on the contrast mechanism, achievable resolution, and acquisition time of the selected modality. Patient condition also affects the practical choice, because the examination must be compatible with the patient's circumstances. The resulting image is most valuable when its structural or functional information directly supports diagnosis, treatment planning, or assessment of change over time.
Clinicians interpret images in relation to a diagnostic question, then use the findings to support diagnosis or plan treatment. Imaging can also reveal whether a condition or injury is changing during follow-up. In procedural settings, the images provide guidance for clinical actions, extending their role beyond initial detection to planning and ongoing management.
A modality is preferred when its physical signal provides information suited to the clinical need and its practical demands are acceptable. For example, clinicians may weigh tissue-dependent radiation attenuation, reflected sound, magnetic-field signals, or radiolabeled-compound distribution according to whether structural or functional information is most relevant. Resolution, speed, patient condition, and radiation risk further influence the choice.
Imaging can characterize injury, support treatment planning, monitor treatment response, and guide procedures. Its contribution therefore changes across the care pathway: an examination may help identify a problem initially, provide information needed to select an intervention, or show how the patient responds afterward. The appropriate outcome depends on the information required at each clinical stage.