Upconversion Nanocapsules
Upconversion Nanocapsules - Related Videos
08:36
Triplet Fusion Upconversion Nanocapsule Synthesis
0 Views •
Cited by 2 •
2022
This protocol details the synthesis of upconversion nanocapsules for subsequent use in photopolymerizable resins for triplet fusion upconversion-facilitated volumetric 3D printing.
11:20
An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
0 Views •
Cited by 1 •
2017
In this protocol, caged protein kinase A (PKA), a cellular signal transduction bioeffector, was immobilized on a nanoparticle surface, microinjected into the cytosol, and activated by the upconverted UV light from near-infrared (NIR) irradiation, inducing downstream stress fiber disintegration in the cytosol.
13:51
Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
0 Views •
Cited by 10 •
2017
A protocol is presented for the synthesis of core-shell lanthanide-doped upconversion nanocrystals (UCNs) and their cellular applications for channel protein regulation upon near-infrared (NIR) light illumination.
10:42
Infrared Degenerate Four-wave Mixing with Upconversion Detection for Quantitative Gas Sensing
0 Views •
2019
Here, we present a protocol to perform sensitive, spatially resolved gas spectroscopy in the mid-infrared region, using degenerate four-wave mixing combined with upconversion detection.
FAQs
The upconversion process begins when lanthanide-doped nanoparticles absorb multiple near-infrared photons rather than one higher-energy photon. Sequential excitation and energy transfer accumulate excitation energy before the material releases it as visible or ultraviolet emission. This mechanism allows near-infrared irradiation to produce an optical signal or activate a light-responsive function while using a lower-energy input.
The nanoparticles provide the light-conversion function, whereas the shell-based capsule architecture accommodates and protects an encapsulated payload. Their combination links optical excitation with cargo transport in one nanoscale platform. This division of roles is important for engineering systems that need both a detectable signal and controlled handling of a chemical or biological payload.
Composition, surface chemistry, and cargo capacity are key design variables. Composition determines the characteristics of the upconversion component, while surface chemistry influences how the capsule interfaces with its surroundings. Cargo capacity affects how much payload the carrier can accommodate. Adjusting these features allows engineers to tailor capsules for tracking, sensing, delivery, or photochemical functions.
A typical design integrates an encapsulated payload with lanthanide-doped nanoparticles inside a shell-based carrier. Engineers can then tune the capsule composition, surface chemistry, and cargo capacity according to the intended function. This integrated arrangement supports systems that combine transport with optical readout, making it possible to monitor a carrier while also using it to handle payloads.
They are useful when a system requires near-infrared irradiation to produce a higher-energy optical response or initiate a light-dependent function. The converted emission can support optical tracking, while the capsule architecture provides a carrier for payloads involved in triggered release. These capabilities make the platform relevant to delivery systems that need both localization and external optical control.
Near-infrared irradiation can penetrate scattering materials more effectively than many shorter wavelengths, providing an advantageous input for engineered capsule systems. After excitation, the upconversion component produces visible or ultraviolet emission that can support biosensing or photochemical treatments. Consequently, the platform connects deeper light delivery with signal generation or treatment-related optical activity.