Bronchial Blockers
Bronchial Blockers - Related Videos
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Cited by 4 •
2010
Bronchial thermoplasty is a non-drug procedure for severe persistent asthma that delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Reducing airway smooth muscle decreases the ability of the airways to constrict, thereby reducing the frequency of asthma attacks.
14:32
Primary Human Bronchial Epithelial Cells Grown from Explants
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Cited by 19 •
2010
Here we describe a detailed method for growing primary human bronchial epithelial cells from explants of human bronchial airway tissue including differentiated growth on an air-liquid interface. This method provides an abundant source of primary cells for investigating the role of the airway epithelium in human lung health and disease.
01:23
The Bronchial Tree
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2025
The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components. The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
09:12
Optimal Lentivirus Production and Cell Culture Conditions Necessary to Successfully Transduce Primary Human Bronchial Epithelial Cells
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Cited by 13 •
2016
Primary human bronchial epithelial cells are difficult to transduce. This protocol describes the production of lentiviruses and their concentration as well as the optimal culture conditions necessary to achieve highly efficient transductions in these cells throughout differentiation to a pseudostratified epithelium.
02:08
Assessing Muscle Contraction with Neuromuscular Blocker Treatment
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2025
This video demonstrates assessing the muscle using cultured motor neurons, Schwann cells, and myotubes, followed by treatment with a neuromuscular blocker to inhibit contraction. Color-coded time-motion graphics show a color-coded time-motion graphic. Red indicates the fastest movement, and blue indicates the slowest.
FAQs
The inflatable cuff creates a localized seal within the selected mainstem or lobar bronchus. Once inflated, it blocks airflow into that region, permitting the targeted lung to deflate while the opposite lung continues receiving ventilation through the single-lumen tube. This selective occlusion produces the separation needed for exposure or containment.
Bronchoscopic guidance is central because the blocker must align with the intended bronchus rather than merely sit somewhere in the airway. Placement checks and continued monitoring help identify malposition, inadequate oxygenation, or airway injury. These safeguards matter because an incorrectly positioned cuff may fail to isolate the desired lung or interfere with ventilation.
The target bronchus determines which lung or lobe is excluded, so selection directly shapes the result. Occluding a mainstem bronchus supports whole-lung separation, whereas occluding a lobar bronchus provides more localized isolation. The cuff therefore controls both the extent of deflation and the anatomical precision of the intervention.
The process begins by placing the blocker under bronchoscopic guidance and directing it toward the intended mainstem or lobar bronchus. After positioning, the cuff is inflated to occlude that airway, allowing the selected lung to deflate while ventilation continues through the tube to the opposite lung. Monitoring then helps detect placement or oxygenation problems.
They are particularly useful during thoracic procedures when collapse of one lung improves the surgeon’s exposure while the other lung remains ventilated. In critical care, lung separation can help limit cross-contamination when disease affects one side. The same approach therefore supports both operative access and management of unilateral pulmonary conditions.
Effective isolation can improve surgical exposure, permit controlled deflation, and reduce movement or contamination from the affected side. Clinicians must also watch for malposition, inadequate oxygenation, and airway injury, because these problems can compromise ventilation or prevent reliable separation. Suction through the blocker may additionally help remove secretions or blood from the isolated airway.