Crude Coal Tar Application

Crude coal tar application is a topical dermatological treatment that uses a complex mixture of coal-derived hydrocarbons to manage inflammatory and hyperproliferative skin disorders. Applied as ointments, creams, shampoos, or bath preparations, coal tar helps slow excessive epidermal cell growth, normalize keratinization, and reduce inflammation, scaling, and itching. Clinicians use it primarily for psoriasis, eczema, and seborrheic dermatitis, often as part of a broader skin-care regimen. Its therapeutic value must be balanced against potential irritation, staining, odor, and increased sensitivity to sunlight, making appropriate formulation, dosing, and patient guidance important in medical practice.

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Research

JoVE EoE - Bacterial Growth and Techniques

Preparation of Crude Cell Extract from Vibrio natriegens

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2025

Source: Wiegand, D. J., et al. Cell-free Protein Expression Using the Rapidly Growing Bacterium Vibrio natriegens. J. Vis. Exp. (2019).This video demonstrates the preparation of a cell extract from Vibrio natriegens, a rapidly growing bacterium known for its high protein synthesis rate. The bacterial pellet is washed and resuspended in lysis buffer before sonication on ice to prevent cellular degradation. The lysate is centrifuged to separate insoluble cell debris, and the cell extract is...

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Cited by 26 •

2013

Psoriasis is a chronic, immune-mediated inflammatory skin disease. The Goeckerman regimen, formulated for the treatment of psoriasis, consists of exposure to ultraviolet B (UVB) light and application of crude coal tar (CCT). The following protocol is for the administration of Goeckerman therapy for the treatment of moderate-to-severe psoriasis.

Cell-Free Protein Expression Using a Bacterial Crude Cell Extract

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2025

Source: Wiegand, D. J., et al. Cell-free Protein Expression Using the Rapidly Growing Bacterium Vibrio natriegens. J. Vis. Exp. (2019).This video demonstrates the use of a bacterial cell-free protein expression system based on Vibrio natriegens crude lysate to perform coupled in vitro transcription and translation. It highlights the preparation of a master mix with essential components and the step-by-step synthesis of functional proteins from a DNA template.

Measurement of H2S in Crude Oil and Crude Oil Headspace Using Multidimensional Gas Chromatography, Deans Switching and Sulfur-selective Detection

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Cited by 11 •

2015

A multidimensional gas chromatography method for the analysis of dissolved hydrogen sulfide in liquid crude oil samples is presented. A Deans switch is used to heart-cut light sulfur gases for separation on a secondary column and detection on a sulfur chemiluminescence detector.

Research

JoVE Journal - Environment
Free Sample

Measurement of the Rheology of Crude Oil in Equilibrium with CO2 at Reservoir Conditions

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Cited by 2 •

2017

A method for measuring the rheology of crude oil in equilibrium with carbon dioxide at reservoir conditions is presented.

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