Implant Surface Damage

Implant surface damage is the alteration or loss of an implant’s outer layer, a clinically important problem because surface condition influences mechanical performance, tissue response, and device longevity. Damage can arise from wear, corrosion, fatigue, scratching, or micromotion at contacting interfaces, which may roughen the surface, release debris or ions, and weaken protective coatings. In medicine, evaluating damaged surfaces through microscopy, materials analysis, and mechanical testing helps researchers identify failure mechanisms and improve implant design, manufacturing, sterilization, and placement. Understanding these changes supports safer orthopedic and dental devices, more reliable tissue integration, and earlier recognition of complications associated with implant degradation.

Implant Surface Damage - Related Videos

Research

JoVE Journal - Medicine

Pilot In Vitro Study to Assess Cleaning Ability and Effects of Different Decontamination Methods on Implant Surfaces

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2025

The present pilot in vitro study aimed to evaluate the cleaning efficacy of three different decontamination tools and possible surface alterations following treatment, using permanent red ink to mimic the presence of oral biofilm.

A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

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Cited by 22 •

2017

Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

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2025

The present protocol describes an experimental model based on ink-staining which can be used for in vitro implant surface decontamination and roughness research to contribute to clinical decision-making.

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C (UV-C) Damage

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Cited by 12 •

2020

This protocol demonstrates the simultaneous detection of reactive oxygen species (ROS), live cells, and dead cells in live primary cultures from mouse ocular surface cells. 2',7'-Dichlorofluoresceindiacetate, propidium iodide, and Hoechst staining are used to assess the ROS, dead cells, and live cells, respectively, followed by imaging and analysis.

Polarization and Characterization of M1 and M2 Human Monocyte-Derived Macrophages on Implant Surfaces

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Cited by 2 •

2024

Here, we present a detailed protocol for assessing the immunomodulatory potential of implant surfaces in vitro, aiming to improve the reliability and reproducibility of current protocols and promoting further research. Secretory cytokine profiles, mRNA expression, and cell surface markers were monitored using blood monocyte-derived macrophages to investigate macrophage polarization cultivated on titanium.

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