Therapy Assessment

Therapy assessment is the systematic evaluation of a patient’s condition, treatment needs, and response to an intervention, helping clinicians make informed decisions about care. It combines clinical history, symptoms, physical examination, diagnostic findings, treatment goals, and observed outcomes to determine whether a therapy is appropriate, effective, and safe. In medicine, therapy assessment supports treatment selection, dose or strategy adjustments, monitoring for adverse effects, and evaluation of functional or quality-of-life changes. Repeated assessment provides evidence for continuing, modifying, or discontinuing treatment and helps align clinical management with patient needs and measurable outcomes.

Therapy Assessment - Related Videos

Research

JoVE EoE - Neurotherapeutics

Performing Electroconvulsive Therapy and Assessing Seizure Efficacy via Pupillary Response

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2025

Source: Shirozu, K., et al. Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy. J. Vis. Exp. (2019)This video demonstrates the procedure for performing electroconvulsive therapy in a human patient, highlighting the stimulation process and assessing seizure activity through pupillary response.

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

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Cited by 4 •

2019

Here, we provide a detailed description of an experimental setup for an analysis of the assessment of DNA integrity in stem cells prior to cell transplantation.

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

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Cited by 5 •

2019

Pupillary responses (light reflex) were measured for assessment of adequate seizure induction by electroconvulsive therapy using an automated infrared pupillometer immediately after electrical stimulation. Constriction ratio was calculated and compared with seizure quality.

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

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Cited by 23 •

2017

Implementation of an orthotopic model of renal cell carcinoma in immunocompetent mice affords the investigator a clinically-relevant system defined by the presence of a primary renal tumor and lung metastases in the same animal. This system can be used to preclinically test a variety of treatments in vivo.

Research

JoVE Journal - Neuroscience
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Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies

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Cited by 21 •

2014

The corticospinal tract, one of the major sensorimotor tracts, can be lesioned unilaterally in the rodent brainstem in order to test neuroplasticity-inducing therapies for the central nervous system. This surgical procedure (“pyramidotomy”) and postoperative assessments are described in this protocol.

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