Electrical Wounding

Electrical wounding is the controlled use of electrical energy to create a localized, reproducible injury for studying how materials, cells, or tissues respond to damage. Its effects depend on the applied voltage or current, pulse duration, electrode arrangement, and surrounding medium; these factors can produce membrane disruption, electrochemical changes, or localized heating. In biophysical research, electrical wounding provides a standardized model for examining wound closure, cell migration, tissue repair, and responses to electric fields. The approach also supports investigations of bioelectric signaling and may inform strategies for electrical stimulation in regenerative medicine and wound-care technologies.

Electrical Wounding - Related Videos

Research

JoVE Journal - Medicine

Demonstration of the Rat Ischemic Skin Wound Model

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Cited by 32 •

2015

The rat, due to its size, availability, and rather docile behavior, has been utilized as a research model for many years. The goal of this protocol is to utilize the rat as an ischemic skin wound healing model to provide valuable insight into the pathophysiology of chronic wounds.

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

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Cited by 6 •

2012

This article provides a detailed and visual description of a methodology for collecting and measuring biochemical inflammatory and nociceptive mediators at the surgical wound site following cesarean delivery. This human bioassay has been used to determine correlations between wound and serum cytokine concentrations and drug-mediated changes in wound cytokines, chemokines and neuropetides.

A New Application of the Electrical Penetration Graph (EPG) for Acquiring and Measuring Electrical Signals in Phloem Sieve Elements

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Cited by 24 •

2015

Electrical Penetration Graph (EPG) is a well-established technique for studying the feeding behavior of stylet-bearing insects. Here we show a new application of EPG as a non-invasive tool for the acquisition of intracellular electrophysiology recordings of sieve elements (SEs), the cells that form the phloem vasculature in plants.

Education

JoVE Science Education - Physics
Free Sample

Electric Potential

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2023

Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Electric potential, also known as "voltage", measures the electric potential energy per unit charge. Electric field is a scalar quantity and is fundamental to many electrical effects. Like potential energy, what is physically meaningful is the difference in the electric potential. For example, the spatial variation in the electric potential is related to the electric...

Murine Model of Wound Healing

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Cited by 207 •

2013

A murine model of cutaneous wound healing that can be used to assess therapeutic compounds in physiological and pathophysiological settings.

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