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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Article DOI: 10.3791/53727-v • 08:23 min • November 13th, 2016
November 13th, 2016 •
1,2,3, 4, 1,5, 1,2,3, 1,2
1Department of Neurology, Harvard Medical School, 2Department of Neurology, Beth Israel Deaconess Medical Center, 3Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, 4Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 5Department of Neurology, Massachusetts General Hospital

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Resting-state functional-connectivity MRI has identified abnormalities in patients with a wide range of neuropsychiatric disorders, including epilepsy due to malformations of cortical development. Transcranial Magnetic Stimulation in combination with EEG can demonstrate that patients with epilepsy have cortical hyperexcitability in regions with abnormal connectivity.

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Multimodal Imaging Stimulation-based Method Connectivity-related Brain Excitability Epilepsy Patients Resting-state Functional Connectivity MRI-guided Transcranial Magnetic Stimulation Simultaneous EEG Recording Cortical Hyperexcitability Epileptogenic Network Cerebral Excitability Cortical Reactivity Diagnosis And Treatment Of Epilepsy Routine EEG Epileptogenic Circuits Tamara Gedankian Research Assistant TMS Target Regions Structural Image Experimental Session
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