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En melanom patient afledt xenograft-model

Article DOI: 10.3791/59508-v • 07:07 min • May 20th, 2019
May 20th, 2019 •
1, 1, 1
1Wistar Institute

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Patient afledte xenograft (PDX) modeller mere robust rekapitulere melanom molekylære og biologiske egenskaber og er mere forudsigende for terapi respons sammenlignet med traditionelle plast vævskultur-baserede assays. Her beskriver vi vores standard Operations protokol for etablering af nye PDX modeller og karakterisering/eksperimenter af eksisterende PDX modeller.

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Kræftforskning melanom patient-afledte xenograft terapi resistens in vivo-modeller metastase
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