Name: Galleria mellonella come modello di screening antimicrobico (Video) | JoVE Journal
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Description: Scopri come ottimizzare i modelli di infezione con Galleria mellonella per valutazioni antimicrobiche precliniche. Questo metodo standardizzato migliora l'affidabilità e riduce i fallimenti clinici.

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<meta charset="utf8"></head><body>Modelli standardizzati di Galleria mellonella per test antimicrobici preclinici

<ol><li>Menard, G., Rouillon, A., Cattoir, V., Donnio, P. Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Galleria+mellonella+as+a+suitable+model+of+bacterial+infection%3A+Past%2C+present+and+future%5BTitle%5D)+AND+%22Front+Cell+Infect+Microbiol%22%5BJournal%5D)">Galleria mellonella as a suitable model of bacterial infection: Past, present and future.</a> Front Cell Infect Microbiol. 11, 782733(2021).</li>
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<li>Tsai, C. J. -Y., Loh, J. M. S., Proft, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Galleria+mellonella+infection+models+for+the+study+of+bacterial+diseases+and+for+antimicrobial+drug+testing%5BTitle%5D)+AND+%22Virulence%22%5BJournal%5D)">Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing.</a> Virulence. 7 (3), 214-229 (2016).</li>
<li>Gallorini, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Immunophenotyping+of+hemocytes+from+infected+Galleria+mellonella+larvae+as+an+innovative+tool+for+immune+profiling%2C+infection+studies+and+drug+screening%5BTitle%5D)+AND+%22Sci+Rep%22%5BJournal%5D)">Immunophenotyping of hemocytes from infected Galleria mellonella larvae as an innovative tool for immune profiling, infection studies and drug screening.</a> Sci Rep. 14, 759(2024).</li>
<li>Smith, F. Q., Casadevall, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fungal+immunity+and+pathogenesis+in+mammals+versus+the+invertebrate+model+organism+Galleria+mellonella%5BTitle%5D)+AND+%22Pathog+Dis%22%5BJournal%5D)">Fungal immunity and pathogenesis in mammals versus the invertebrate model organism Galleria mellonella.</a> Pathog Dis. 79 (3), ftab013(2021).</li>
<li>Sugumaran, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparative+biochemistry+of+eumelanogenesis+and+the+protective+roles+of+phenoloxidase+and+melanin+in+insects%5BTitle%5D)+AND+%22Pigment+Cell+Res%22%5BJournal%5D)">Comparative biochemistry of eumelanogenesis and the protective roles of phenoloxidase and melanin in insects.</a> Pigment Cell Res. 15 (1), 2-9 (2002).</li>
<li>Sheehan, G., Garvey, A., Croke, M., Kavanagh, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Innate+humoral+immune+defences+in+mammals+and+insects%3A+The+same%2C+with+differences%5BTitle%5D)+AND+%22Virulence%22%5BJournal%5D)">Innate humoral immune defences in mammals and insects: The same, with differences.</a> Virulence. 9, 1625-1639 (2018).</li>
<li>Wright, C. L., Kavanagh, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Galleria+mellonella+as+a+novel+in+vivo+model+to+screen+natural+product-derived+modulators+of+innate+immunity%5BTitle%5D)+AND+%22Appl+Sci%22%5BJournal%5D)">Galleria mellonella as a novel in vivo model to screen natural product-derived modulators of innate immunity.</a> Appl Sci. 12 (13), 6587(2022).</li>
<li>Newton, S. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+the+invertebrate+Galleria+mellonella+as+an+infection+model+to+study+the+Mycobacterium+tuberculosis+complex%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Use of the invertebrate Galleria mellonella as an infection model to study the Mycobacterium tuberculosis complex.</a> J Vis Exp. (148), e59703(2019).</li>
<li>Frankel, G., Collins, J. W., Schroeder, G. N., Harding, C. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+Galleria+mellonella+as+a+model+organism+to+study+Legionella+pneumophila+infection%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Use of Galleria mellonella as a model organism to study Legionella pneumophila infection.</a> J Vis Exp. (81), e50964(2013).</li>
<li>Romera, D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+Galleria+mellonella+infection+model+as+a+system+to+investigate+the+virulence+of+Candida+auris+strains%5BTitle%5D)+AND+%22Pathog+Dis%22%5BJournal%5D)">The Galleria mellonella infection model as a system to investigate the virulence of Candida auris strains.</a> Pathog Dis. 78 (9), ftaa067(2020).</li>
<li>Kwadha, C. A., Ong'amo, G. O., Ndegwa, P. N., Raina, S. K., Fombong, A. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+biology+and+control+of+the+greater+wax+moth%2C+Galleria+mellonella%5BTitle%5D)+AND+%22Insects%22%5BJournal%5D)">The biology and control of the greater wax moth, Galleria mellonella.</a> Insects. 8 (2), 61(2017).</li>
<li>Miles, A. A., Misra, S. S., Irwin, J. O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+estimation+of+the+bactericidal+power+of+the+blood%5BTitle%5D)+AND+%22J+Hyg%22%5BJournal%5D)">The estimation of the bactericidal power of the blood.</a> J Hyg. 38, 732-749 (1938).</li>
<li>Ignasiak, K., Maxwell, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Galleria+mellonella+%28greater+wax+moth%29+larvae+as+a+model+for+antibiotic+susceptibility+testing+and+acute+toxicity+trials%5BTitle%5D)+AND+%22BMC+Res+Notes%22%5BJournal%5D)">Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials.</a> BMC Res Notes. 10 (1), 428(2017).</li>
<li>Hesketh-Best, P. J., Mouritzen, M. V., Shandley-Edwards, K., Billington, R. A., Upton, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Galleria+mellonella+larvae+exhibit+a+weight-dependent+lethal+median+dose+when+infected+with+methicillin-resistant+Staphylococcus+aureus%5BTitle%5D)+AND+%22Pathog+Dis%22%5BJournal%5D)">Galleria mellonella larvae exhibit a weight-dependent lethal median dose when infected with methicillin-resistant Staphylococcus aureus.</a> Pathog Dis. 79 (2), ftab003(2021).</li>
<li>Mahenthiralingam, E., Weiser, R., Floto, R. A., Davies, J. C., Fothergill, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Selection+of+relevant+bacterial+strains+for+novel+therapeutic+testing%3A+a+Guidance+document+for+priority+cystic+fibrosis+lung+pathogens%5BTitle%5D)+AND+%22Curr+Clin+MicrobiolRep%22%5BJournal%5D)">Selection of relevant bacterial strains for novel therapeutic testing: a Guidance document for priority cystic fibrosis lung pathogens.</a> Curr Clin MicrobiolRep. 9 (4), 33-45 (2022).</li>
<li>Carter, M. E. K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+subtype+of+a+Pseudomonas+aeruginosa+cystic+fibrosis+epidemic+strain+exhibits+enhanced+virulence+in+a+murine+model+of+acute+respiratory+infection%5BTitle%5D)+AND+%22J+Infect+Dis%22%5BJournal%5D)">A subtype of a Pseudomonas aeruginosa cystic fibrosis epidemic strain exhibits enhanced virulence in a murine model of acute respiratory infection.</a> J Infect Dis. 202 (6), 935-942 (2010).</li>
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<li>Reyhanoglu, G., Reddivari, A. K. R. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aReyhanoglu%2C+G+%22Tobramycin%22">Tobramycin</a>. , StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK551695/ (2023).</li>
<li>Crass, R. L., Rutter, W. C., Burgess, D. R., Martin, C. A., Burgess, D. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Nephrotoxicity+in+patients+with+or+without+cystic+fibrosis+treated+with+polymyxin+b+compared+to+colistin%5BTitle%5D)+AND+%22Antimicrob+Agents+Chemother%22%5BJournal%5D)">Nephrotoxicity in patients with or without cystic fibrosis treated with polymyxin b compared to colistin.</a> Antimicrob Agents Chemother. 61 (4), e02329-e02416 (2017).</li>
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<li>Prasad, N. K., Seiple, I. B., Cirz, R. T., Rosenberg, O. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Leaks+in+the+pipeline%3A+A+failure+analysis+of+gram-negative+antibiotic+development+from+2010+to+2020%5BTitle%5D)+AND+%22Antimicrob+Agents+Chemother%22%5BJournal%5D)">Leaks in the pipeline: A failure analysis of gram-negative antibiotic development from 2010 to 2020.</a> Antimicrob Agents Chemother. 66 (5), e0005422(2022).</li>
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</ol>

<table><tbody><tr><td>Calibro 22s, ago piccolo RN a mozzi, 2 pollici, punta stile 2</td><td>Hamilton</td><td>7758-03</td><td>Sostituzione della siringa Hamilton.</td></tr><tr><td>Azioni per infezioni batteriche</td><td></td><td></td><td>Scorte batteriche di densità nota (CFU/mL) congelate durante la fase di crescita a metà esponenziale.</td></tr><tr><td>Etanolo</td><td>Fisher Scientific</td><td>10610813</td><td>Possono essere utilizzati altri produttori.</td></tr><tr><td>Larve di G. mellonella</td><td>Cibi vivi</td><td>5.06045E+12</td><td>Per questo fornitore, gli ordini sono contrassegnati come " Nuovo materiale per uso in laboratorio". Ad aprile 2024, il nuovo stock viene consegnato al fornitore il lunedì. Gli ordini dovrebbero essere effettuati allora, per la consegna il mercoledì.</td></tr><tr><td>Siringa a microlitri</td><td>Hamilton</td><td>80630</td><td>La siringa 80630 ha una 100 & micro; L capacità. Esistono altri volumi, come gli 80430, 80530 o 80730.</td></tr><tr><td>Piastra di Petri</td><td>Fisher Scientific</td><td>12674785</td><td>Possono essere utilizzati altri produttori.</td></tr></tbody></table>

galleria mellonella come modello di screening antimicrobico

Galleria mellonella as an Antimicrobial Screening Model

Galleria mellonella come modello di screening antimicrobico

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Galleria mellonella come modello di screening antimicrobico

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