Optical Ultrasound Detection
Optical Ultrasound Detection - Related Videos
08:31
Three-dimensional Optical-resolution Photoacoustic Microscopy
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Cited by 27 •
2011
Optical-resolution photoacoustic microscopy (OR-PAM) is an emerging technology capable of imaging optical absorption contrasts in vivo with cellular resolution and sensitivity. Here, we provide a visualized instruction on the experimental protocols of OR-PAM, including system configuration, system alignment, typical in vivo experimental procedures, and functional imaging schemes.
10:21
Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
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Cited by 18 •
2016
Multicolor fluorescence detection in droplet microfluidics typically involves bulky and complex epifluorescence microscope-based detection systems. Here we describe a compact and modular multicolor detection scheme that utilizes an array of optical fibers to temporally encode multicolor data collected by a single photodetector.
08:53
Label-free Single Molecule Detection Using Microtoroid Optical Resonators
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Cited by 32 •
2015
We have developed a label-free biosensing system based on optical resonator technology known as Frequency Locking Optical Whispering Evanescent Resonator (FLOWER) that is capable of detecting single molecules in solution. Here the procedures behind this work are described and presented.
06:09
Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
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Cited by 1 •
2023
Point-of-care ultrasound (POCUS) of the optic nerve sheath diameter (ONSD) has been shown to be useful in identifying patients with increased intracranial pressure (ICP). However, the non-standardized technique for this POCUS has hampered its use. We present a standardized image acquisition protocol for use in the acute care setting.
08:21
Wideband Optical Detector of Ultrasound for Medical Imaging Applications
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Cited by 4 •
2014
Optical detection of ultrasound is impractical in many imaging scenarios because it often requires stable environmental conditions. We demonstrate an optical technique for ultrasound sensing in volatile environments with miniaturization and sensitivity levels appropriate for optoacoustic imaging in restrictive scenarios, e.g. intravascular applications.
FAQs
The acoustic wave can be sensed through several optical changes: it may alter a material’s refractive index, change the light’s path length, or displace a membrane. Those perturbations modulate reflected or transmitted light in intensity, phase, or wavelength. Selecting the optical quantity that changes provides a route to convert pressure-wave behavior into a measurable signal.
These approaches monitor different optical responses to the same acoustic disturbance. Laser interferometry can track changes in optical phase or path length, fiber-optic configurations guide light through compact sensing structures, and optical resonators can respond through changes in resonant behavior. Their inclusion gives designers multiple ways to match signal readout with a bioengineering device’s form factor.
Optical detection can provide electromagnetic immunity, which is useful when electrical interference could affect measurements. It also supports compact geometries and flexible form factors, including fiber-based configurations. These properties make the approach attractive for sensing arrangements that are difficult to realize with conventional piezoelectric transducers, particularly when integration with biomedical devices or minimally invasive probes is important.
The reported quantity depends on which optical property the acoustic wave changes and how the system reads that change. A refractive-index or path-length variation may appear through phase, while membrane motion or other optical interactions may modulate transmitted or reflected intensity or wavelength. The selected readout therefore determines how the measured optical signal represents the acoustic pressure wave.
First, an ultrasound wave interacts with the optical sensing structure or material. The interaction changes refractive index, optical path length, or membrane position. Light reflected from or transmitted through that structure then carries a change in intensity, phase, or wavelength. Converting that optical variation produces either a quantitative pressure measurement or spatially resolved image.
Bioengineering applications include photoacoustic imaging, minimally invasive probes, and high-frequency ultrasound sensing. The method can also support integration with biomedical devices because optical components offer compact and flexible configurations. Depending on the system design, the resulting readout can provide spatially resolved images, quantitative pressure measurements, or both.
The primary outputs are optical signals that can be interpreted as quantitative acoustic pressure measurements or transformed into spatially resolved images. This makes the approach relevant to experiments requiring information about ultrasound fields or photoacoustic responses. Its electromagnetic immunity, compact form factors, and potential device integration further support use in biomedical measurement platforms.