Thread Mechanics

Thread mechanics is the study of how forces, motion, friction, and stresses act in threaded components such as bolts, nuts, and power screws. A thread’s helical profile converts rotational motion into axial movement, while torque generates clamping force or drives a load; friction at the contacting flanks and under bearing surfaces strongly influences efficiency, preload, and self-locking behavior. Engineers use thread mechanics to select dimensions and materials, control fastener tightening, and predict failure modes such as stripping, yielding, loosening, and fatigue. These principles support reliable designs in machinery, structures, manufacturing systems, and mechanical power-transmission devices.

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JoVE EoE - Neuropathology

Inducing Ischemic Stroke via Middle Cerebral Artery Occlusion Using a Thread Bolt

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2025

This video demonstrates the process of inducing ischemic stroke in a rat model by occluding the middle cerebral artery (MCA) using a thread bolt. The procedure involves ligating the carotid arteries, inserting a thread bolt into the external carotid artery, and blocking blood flow from the MCA to the brain, leading to neuronal death and mimicking an ischemic stroke.

Quantification of Tear Volume in an Autoimmune Dry Eye Rat Model using the Phenol Red Thread

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2025

This video demonstrates the phenol red thread test to determine tear volume in an autoimmune dry eye rat model. The pH-sensitive acidic phenol red thread changes color when it comes in contact with the alkaline tears. The shorter length of color change in the phenol red thread corresponds to reduced tear volume.

Phenol Red Thread-based Sampling Procedure for Untargeted Tear Fluid Lipidomics in Biomarker Discovery

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2025

This protocol describes a unique clinical protocol for collecting human tear fluid samples using phenol red threads and liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based workflow to discover the tear lipidomic profile. The simple methyl tert-butyl ether (MTBE)/methanol biphasic separation method enables rapid tear lipid extraction with high recovery for tear biomarker discovery.

Operation Procedure and Precautions of Thread-Embedding Acupuncture Therapy in Alzheimer

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2024

This study presents a protocol for thread-embedding acupuncture therapy in Alzheimer's disease-like rats.

Mechanical Stimulation of Chondrocyte-agarose Hydrogels

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Cited by 29 •

2012

The biosynthesis of cartilaginous extracellular matrix by chondrocytes can be affected by application of mechanical stimuli. This method describes the technique of applying dynamic compressive strains to chondrocytes encapsulated in 3D constructs and the evaluation of induced changes in chondrocyte metabolism.

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