Biopolymer Carriers

Biopolymer carriers are delivery systems made from naturally derived or biologically compatible polymers that transport therapeutic molecules through the body while helping control their stability, distribution, and release. They can encapsulate drugs or bind them within a polymer matrix, where diffusion, swelling, or gradual biodegradation governs how the payload becomes available under physiological conditions. In medicine, these carriers support controlled drug delivery, improve the handling of poorly soluble or unstable compounds, and can help concentrate treatment at selected tissues. Their composition and architecture also enable applications in vaccines, nucleic-acid delivery, regenerative medicine, and personalized therapies.

Biopolymer Carriers - Related Videos

Research

JoVE Journal - Chemistry
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Preparation of Biopolymer Aerogels Using Green Solvents

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Cited by 44 •

2016

A new way for the production of biopolymer-based aerogels by carbon dioxide (CO2) induced gelation is shown. The technique utilizes pressurized carbon dioxide (5 MPa) for the production of biopolymer hydrogels and supercritical CO2 (12 MPa) to convert gels into aerogels. The only solvents needed besides CO2 are water and ethanol.

Research

JoVE Journal - Bioengineering

Methods for the Self-integration of Megamolecular Biopolymers on the Drying Air-LC Interface

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Cited by 4 •

2017

A method for the drying-induced self-integration of megamolecular biopolymers on the air-liquid crystalline interface is provided here. This methodology will be useful not only for understanding the macroscopic potentials of biopolymers, but also as an evaluation method for soft materials in biomedical and environmental fields.

Education

JoVE Core - Biology

Electron Carriers

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2019

Electron carriers can be thought of as electron shuttles. These compounds can easily accept electrons (i.e., be reduced) or lose them (i.e., be oxidized). They play an essential role in energy production because cellular respiration is contingent on the flow of electrons. Over the many stages of cellular respiration, glucose breaks down into carbon dioxide and water. Electron carriers pick up electrons lost by glucose in these reactions, temporarily storing and releasing them into the electron...

Thermally Responsive Biopolymer-Based Inhibition of Tumor Progression in a Rat Model

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2025

Begin with an anesthetized rat bearing a brain tumor composed of proliferating tumor cells.Expose the rat’s skull and create a hole to reveal the brain region with the tumor.Take a thermally responsive biopolymer fused with a cell-penetrating peptide and an inhibitor of c-myc, an oncogenic protein.Inject the biopolymer into the femoral vein of the hind limb for delivery to the brain.Apply infrared light through the skull hole to heat the tumor site, which induces biopolymer aggregation along...

Molecular Entanglement and Electrospinnability of Biopolymers

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Cited by 13 •

2014

Electrospinning is a fascinating technique used to fabricate micro- to nano-scale fibers from a wide variety of materials. Molecular entanglement of the constituent polymers in the spinning dope is essential for successful electrospinning. We present a protocol for utilizing rheology to evaluate the electrospinnability of two biopolymers, starch and pullulan.

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