Spinal Instability

Spinal instability is the abnormal movement or loss of structural control within a spinal motion segment, potentially causing pain, deformity, or neurological impairment. It occurs when the vertebrae, intervertebral discs, facet joints, ligaments, or supporting muscles cannot maintain normal alignment during physiological loading, often after trauma, degeneration, or surgery. Clinicians assess instability through symptoms, physical examination, and imaging, including dynamic radiographs and magnetic resonance imaging when neural structures are involved. Accurate identification guides decisions about rehabilitation, bracing, medication, or surgical stabilization, helping prevent progressive deformity and protect spinal cord and nerve function.

Spinal Instability - Related Videos

Education

JoVE Core - Cell Biology

Microtubule Instability

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2023

Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound tubulin subunits form αβ-heterodimers for microtubule assembly. These core building blocks interact longitudinally, polymerizing into protofilaments. The protofilaments then interact with one another through lateral bonding forces to form stable cylindrical microtubules. These cylindrical filaments are dynamic as they undergo repeated assembly and...

Microtubule Instability

0 Views •

2021

Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound tubulin subunits form αβ-heterodimers for microtubule assembly. These core building blocks interact longitudinally, polymerizing into protofilaments. The protofilaments then interact with one another through lateral bonding forces to form stable cylindrical microtubules. These cylindrical filaments are dynamic as they undergo repeated assembly and...

Research

JoVE Journal - Engineering

Magnetically Induced Rotating Rayleigh-Taylor Instability

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Cited by 5 •

2017

We present a protocol for preparing a two-layer density-stratified liquid that can be spun-up into solid body rotation and subsequently induced into Rayleigh-Taylor instability by applying a gradient magnetic field.

Research

JoVE Journal - Behavior
Free Sample

Assessing Forelimb Function after Unilateral Cervical SCI using Novel Tasks: Limb Step-alternation, Postural Instability and Pasta Handling

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Cited by 9 •

2013

Three new behavioral tests (forelimb step-alternation, postural instability test, pasta handling test) for evaluating forelimb function after cervical spinal cord injury in rodents are described.

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Cited by 55 •

2012

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

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