実験的炎症性腸病気のマウスモデルで使用するため、腸管へのホーミングを増加するヒト間葉系幹細胞の超音波ガイド下心臓内注射
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September 01, 2017
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概要
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間葉系幹細胞 (MSC) の小さい割合 (1-5%) が静脈注射または腹腔内炎症コロン1,2ホーム大腸炎症モデルにおけるマウスの調査は示した。本研究は、MSCs の超音波ガイド下心臓内注射が腸への増加のローカリゼーションの結果することを示しています。
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Cite this Article
Dave, M., Menghini, P., Sugi, K., Somoza, R. A., Lee, Z., Jain, M., Caplan, A., Cominelli, F. Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases. J. Vis. Exp. (127), e55367, doi:10.3791/55367 (2017).
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