再生末梢神経インターフェース:切断後の痛みにおけるランダム化比較試験のための外科的プロトコル

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5 件の引用

03:53 分

2024年3月15日

10.3791/66378-v

2024年3月15日

4.3K 回視聴

Emily Pettersen¹^,²^,³^,⁴ , Paolo Sassu⁵ , Francesca Alice Pedrini¹^,⁵ , Hannes Granberg¹^,² , Carina Reinholdt²^,⁶ , Juan Manuel Breyer⁷ , Aidan Roche⁸ , Andrew Hart⁹^,¹⁰ , Adil Ladak¹¹ , Hollie A. Power¹¹ , Michael Leung¹² , Michael Lo¹² , Ian Valerio¹³ , Kyle R. Eberlin¹³ , Jason Ko¹⁴ , Gregory A. Dumanian¹⁴ , Theodore A. Kung¹⁵ , Paul Cederna¹⁵ , Max Ortiz-Catalan¹^,⁴^,¹⁶^,¹⁷

¹Center for Bionics and Pain Research, ²Center for Advanced Reconstruction of Extremities, Sahlgrenska University Hospital, ³Department of Electrical Engineering, Chalmers University of Technology, ⁴Bionics Institute, ⁵IV Clinica Ortoplastica, IRCCS Istituto Ortopedico Rizzoli, ⁶Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, ⁷Department of Orthopedic Surgery, Hand Unit, Worker Hospital, ⁸College of Medicine and Veterinary Medicine, The Queen's Medical Research Institute, The University of Edinburgh, ⁹Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, ¹⁰College of Medicine, Veterinary & Life Sciences, The University of Glasgow, ¹¹Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, ¹²Plastics and Reconstructive Surgery, Dandenong Hospital, Monash Health, ¹³Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital & Harvard Medical School, ¹⁴Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, ¹⁵Section of Plastic Surgery, Department of Surgery, Michigan Medicine, ¹⁶Medical Bionics Department, University of Melbourne, ¹⁷Prometei Pain Rehabilitation Center

ここでは、切断後の神経障害性疼痛を治療するための再生末梢神経インターフェース(RPNI)手術を行う外科的処置について、国際的なランダム化比較試験(RCT)の文脈で説明します(ClinicalTrials.gov、NCT05009394)。このRCTでは、RPNIを他の2つの外科的技術、すなわち標的筋再神経支配(TMR)および神経腫切除と筋肉内転位と組み合わせたものと比較しています。

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0:00

Introduction

1:13

Surgical Procedure for Regenerative Peripheral Nerve Interface (RPNI) for Neuroma Management