Mass Determination
Mass Determination - Related Videos
07:30
Determining the Mass Percent Composition in an Aqueous Solution
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2023
Source: Laboratory of Dr. Neal Abrams — SUNY College of Environmental Science and Forestry Determining the composition of a solution is an important analytical and forensic technique. When solutions are made with water, they are referred to as being aqueous, or containing water. The primary component of a solution is referred to as the solvent, and the dissolved minor component is called the solute. The solute is dissolved in the solvent to make a solution. Water is the most common solvent in...
01:24
Determination of Molar Masses of Polymers I
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2026
Polymerization produces macromolecules with a range of chain lengths due to the random nature of molecular growth processes. As chains form and terminate at different stages, a single polymer sample contains molecules of varying sizes rather than a uniform structure. This variability is described using average molar masses and distribution-related parameters, which together provide a comprehensive understanding of polymer characteristics.The distribution of molar masses plays a critical role in...
01:27
Determination of Molar Masses of Polymers II
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2026
Polymer samples typically consist of macromolecular chains with a distribution of lengths, resulting in a range of molar masses rather than a single discrete value. Conventional descriptors such as the number-average molar mass and weight-average molar mass quantify this distribution but do not fully capture polymer behavior in solution..The viscosity-average molar mass provides a more realistic description of polymer behavior in solution because it accounts for the enhanced contribution of...
09:26
Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication
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Cited by 4 •
2016
We present a protocol for identifying and quantifying the components in mixtures of species possessing similar proteins. Mass spectrometry detects peptides for identification, and gives relative quantitation by ratios of peak areas. As a tool food for fraud detection, the method can detect 1% horse in beef.
10:17
Rapid Determination of Antibody-Antigen Affinity by Mass Photometry
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Cited by 14 •
2021
We describe a single-molecule approach to antigen-antibody affinity measurements using mass photometry (MP). The MP-based protocol is fast, accurate, uses a very small amount of material, and does not require protein modification.
FAQs
A calibrated balance compares the force exerted by a sample under gravity with a reference or internal compensation system. Calibration helps establish a reliable relationship between the instrument’s response and the sample’s mass. This consistency allows chemists to use measured values in quantitative composition, stoichiometric calculations, and preparation of chemical solutions.
Drafts, vibration, temperature changes, and moisture can interfere with reliable measurements. These influences may disturb the balance, alter the sample, or affect the measurement conditions during weighing. Careful handling and controlled surroundings reduce such effects, improving reproducibility when mass values are used to calculate reactant amounts, product yield, or analyte concentration.
Direct weighing measures the material placed on the balance, while weighing by difference determines the amount transferred by comparing container masses before and after the transfer. Gravimetric methods use mass measurements to determine quantities such as product yield or analyte concentration. The appropriate approach depends on the chemical measurement objective.
Chemists should use a calibrated balance and handle the sample carefully while minimizing drafts, vibration, temperature effects, and moisture exposure. These controls help preserve the reliability of the reading rather than treating the displayed value as automatically accurate. Consistent handling is especially important when measured masses support preparation or reaction analysis.
Weighing by difference is useful when the quantity delivered from a container matters more than the mass initially placed on the balance. Comparing the container’s mass before and after transfer provides the transferred amount. This approach supports controlled preparation and helps connect the measured material directly with a reaction or solution.
Mass values provide the quantitative basis for determining how much reactant is used and for preparing chemical solutions with defined amounts of material. They also support comparisons between reactants and products during reaction analysis. Because these calculations depend on measured quantities, reliable weighing contributes directly to reproducible chemical work.