Pseudo-ternary Phase

A pseudo-ternary phase diagram is a graphical tool that represents the phase behavior of a three-component formulation system, often used to design pharmaceutical delivery systems. It treats a surfactant and cosurfactant mixture as a single pseudocomponent and maps how changing the proportions of oil, aqueous phase, and this mixture produces distinct regions, such as microemulsions, emulsions, or separated phases. Researchers commonly construct diagrams by varying component ratios and identifying phase changes through visual inspection or analytical methods. In medicine, these diagrams guide the selection of stable compositions for improving drug solubilization, bioavailability, administration, and controlled delivery.

Pseudo-ternary Phase - Related Videos

Education

JoVE Core - Physical Chemistry

Phase Diagrams of Ternary Systems

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2026

Consider a ternary system, which is composed of three components: water (W), ethanoic acid (E), and trichloromethane (T). Here, Ethanoic acid (E) is fully miscible with both water (W) and trichloromethane (T), meaning it can mix entirely with either of them. However, water and trichloromethane have partial miscibility, meaning they can only mix to a certain extent, beyond which two separate phases will form.The phase diagram of a ternary system is represented as an equilateral triangle, where...

Single Phase Inverter

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2023

Source: Ali Bazzi, Department of Electrical Engineering, University of Connecticut, Storrs, CT. DC power is unidirectional and flows in one direction, whereas, AC current alternates directions at a frequency of 50-60 Hz. Most common electronic devices are designed to run off of AC power; therefore an input DC source must be inverted to AC. Inverters convert DC voltage to AC through switching action that repeatedly flips the polarity of the input DC source at the output or load side for part of...

Research

JoVE Journal - Chemistry
Free Sample

Preparation of Binary and Ternary Deep Eutectic Systems

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Cited by 19 •

2019

This protocol aims to standardize the preparation of deep eutectic systems throughout the scientific community so that these systems can be reproduced.

Phase Diagrams

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2020

A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...

Phase Transitions

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2020

Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to occupy...

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