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Bioengineering

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3D Magnetic Stem Cell Aggregation und Bioreactor Ausreifung für Knorpelregeneration

Article DOI: 10.3791/55221-v • 09:46 min • April 27th, 2017
April 27th, 2017 •
1, 1, 1
1Laboratoire Matière et Systèmes Complexes (MSC), UMR 7057 CNRS and University Paris Diderot

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Chondrogenese aus Stammzellen erfordert Feinabstimmung der Kulturbedingungen. Hier präsentieren wir einen magnetischen Ansatz für Zellen Kondensation, ein wesentlicher Schritt Chondrogenese zu initiieren. Darüber hinaus zeigen wir, dass dynamische Reifung in einem Bioreaktor mechanische Stimulation auf die Zellkonstrukte und verbessert knorpelige extrazelluläre Matrixproduktion gilt.

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Bioengineering Ausgabe 122 Magnetkräfte magnetische mesenchymalen Stammzellen Knorpeldefekts Chondrogenese Bioreaktor Tissue Engineering
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