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Vurdering af dopaminerge homøostase i mus ved hjælp af High-performance væskekromatografi analyse og Synaptosomal dopamin optagelse
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Vurdering af dopaminerge homøostase i mus ved hjælp af High-performance væskekromatografi analyse og Synaptosomal dopamin optagelse

Article DOI: 10.3791/56093-v • 11:26 min • September 21st, 2017
September 21st, 2017 •
1, 1, 2, 1, 1
1Molecular Neuropharmacology and Genetics Laboratory, Lundbeck Foundation Center for Biomembranes in Nanomedicine, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen and Department of Neuroscience and Pharmacology, University of Copenhagen

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Synaptosomal dopamin optagelse og højtydende væskekromatografi analyse repræsenterer eksperimentelle værktøjer til at undersøge dopamin homøostase i mus ved at vurdere funktionen af dopamin-transporter og niveauer af dopamin i striatal væv, henholdsvis. Her præsenterer vi protokoller for at måle dopamin væv indhold og vurdere funktionaliteten af dopamin-transporter.

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Neurovidenskab sag 127 Striatum dopamin high-performance væskekromatografi (HPLC) synaptosomal dopamin optagelse synaptosomes dopamin homøostase dopamin transporter
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