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Journal / Cancer Research / Un sistema de cultivo timático tridimensional…
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Cancer Research

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Un sistema de cultivo timático tridimensional para generar emigrantes timémicos específicos de células madre pluripotentes inducidos por la murino

Article DOI: 10.3791/58672-v • 10:44 min • August 9th, 2019
August 9th, 2019 •
*1,2, *1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1, 3, 1,2
1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH
* These authors contributed equally

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Este artículo describe un método novedoso para generar antígenos tumorales inducidos por células madre pluripotentes inducidas por antígenos timáticos (iTE) por un sistema de cultivo timico tridimensional (3D). iTE son un subconjunto homogéneo de células T estrechamente relacionadas con células T ingenuas con la capacidad de proliferación, formación de la memoria y supresión tumoral.

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Cancer Research Número 150 Célulamadre madre células madre pluripotentes inducidas inmunología transferencia de células adoptivas diferenciación de células T especificidad del antígeno tumoral cultivo 3D cultivo de órganos timicos fetales
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