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Journal / Cancer Research / Трехмерная сфероидная модель для исследования…
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Трехмерная сфероидная модель для исследования опухоле-стромального взаимодействия при гепатоцеллюлярной карциноме
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Трехмерная сфероидная модель для исследования опухоле-стромального взаимодействия при гепатоцеллюлярной карциноме

Article DOI: 10.3791/62868-v • 12:24 min • September 30th, 2021
September 30th, 2021 •
*1,2, *2, 2, 2, *3, *4,5
1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust
* These authors contributed equally

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Отсутствуют комплексные модели in vitro , которые точно повторяют соответствующие заболевания человека. В текущем исследовании представлено трехмерное (3D) создание и культура сфероидов опухолей, надежный инструмент in vitro для изучения опухолево-стромального взаимодействия при гепатоцеллюлярной карциноме человека.

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