재생 말초 신경 인터페이스: 절단 후 통증에 대한 무작위 대조 시험을 위한 수술 프로토콜

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5회 인용됨

03:53 분

2024년 3월 15일

10.3791/66378-v

2024년 3월 15일

4.3K 조회수

Emily Pettersen¹^,²^,³^,⁴ , Paolo Sassu⁵ , Francesca Alice Pedrini¹^,⁵ , Hannes Granberg¹^,² , Carina Reinholdt²^,⁶ , Juan Manuel Breyer⁷ , Aidan Roche⁸ , Andrew Hart⁹^,¹⁰ , Adil Ladak¹¹ , Hollie A. Power¹¹ , Michael Leung¹² , Michael Lo¹² , Ian Valerio¹³ , Kyle R. Eberlin¹³ , Jason Ko¹⁴ , Gregory A. Dumanian¹⁴ , Theodore A. Kung¹⁵ , Paul Cederna¹⁵ , Max Ortiz-Catalan¹^,⁴^,¹⁶^,¹⁷

¹Center for Bionics and Pain Research, ²Center for Advanced Reconstruction of Extremities, Sahlgrenska University Hospital, ³Department of Electrical Engineering, Chalmers University of Technology, ⁴Bionics Institute, ⁵IV Clinica Ortoplastica, IRCCS Istituto Ortopedico Rizzoli, ⁶Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, ⁷Department of Orthopedic Surgery, Hand Unit, Worker Hospital, ⁸College of Medicine and Veterinary Medicine, The Queen's Medical Research Institute, The University of Edinburgh, ⁹Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, ¹⁰College of Medicine, Veterinary & Life Sciences, The University of Glasgow, ¹¹Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, ¹²Plastics and Reconstructive Surgery, Dandenong Hospital, Monash Health, ¹³Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital & Harvard Medical School, ¹⁴Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, ¹⁵Section of Plastic Surgery, Department of Surgery, Michigan Medicine, ¹⁶Medical Bionics Department, University of Melbourne, ¹⁷Prometei Pain Rehabilitation Center

여기에서는 국제 무작위 대조 시험(RCT)의 맥락에서 절단 후 신경병증성 통증을 치료하기 위한 재생말초신경계(RPNI) 수술을 수행하는 수술 절차를 설명합니다(ClinicalTrials.gov, NCT05009394). 무작위배정 비교임상시험연구는 RPNI를 두 가지 다른 수술 기법, 즉 표적 근육 재신경 박제(Targeted Muscle Reneural vation, TMR) 및 근육 내 전위(intra-muscular transposition)와 결합된 신경종 절제술과 비교한다.

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Chapters in this video

0:00

Introduction

1:13

Surgical Procedure for Regenerative Peripheral Nerve Interface (RPNI) for Neuroma Management