A significant portion of the human genome is transcribed into RNA, which are versatile molecules that perform essential cellular functions. They facilitate the transfer of genetic information for protein synthesis, participate in the translation process, regulate gene expression at various levels, and are involved in sensing environmental changes and signal transduction. The diverse functions of RNA are primarily determined by their interactions with macromolecules, such as proteins, other RNA molecules, DNA, lipids, metabolites, and carbohydrates. Understanding these interactions is crucial for unraveling the roles of RNA in cellular processes, gene regulation, and disease mechanisms. This collection aims to compile various approaches for investigating the RNA interactome, both specifically and broadly.

This collection will feature techniques like RNA antisense purification, RNA interactome capture, and in vitro methods for studying RNA interactions with binding partners. It will also cover structural biology approaches and computational tools. Additionally, we are interested in modifications of established techniques that can enhance experimental methods to meet specific goals. These improvements may focus on increasing sensitivity and specificity, managing complex systems, or streamlining workflows.