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TOPICAL COLLECTIONS

Animal Models of Neurodegenerative Diseases

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Ricardo Augusto Leoni de Sousa

Ricardo Augusto Leoni de Sousa

Universidade Federal dos Vales do Jequitinhonha e Mucuri

<p>Dr. Ricardo Augusto Leoni De Sousa received his PhD in Pharmaceutical Science from Federal University of Rio de Janeiro in 2018, where he developed a new gestational diabetes model in mice, and investigated how this new model would affect the brain and behavior of the offspring. He is conducting his Postdoctoral research in the Program of Physiological Science from Federal University of Jequitinhonha and Mucuri Valleys, where he initially investigated how physical exercise during a gestation infected with zika virus could affect the brain and behavior of mice pups. Nowadays, he has been working in projects involving different neurodegenerative diseases, and the usage of physical exercise as a non-pharmacological intervention on these pathologies. Dr. Ricardo Augusto Leoni De Sousa is a neuroscientist and his research focuses on investigating how physical exercise influences neuroinflammation and affects brain and behavior in different neurodegenerative diseases. He is a member of the Society for Neuroscience, where he participated of the Latin American Training Program 2019-2020.&nbsp; The main topics of his scientific research are: neurodegenerative and metabolic diseases; memory and cognitive function; anxiety and depression; physical activity and health.</p>

Collection Overview

This collection aims to present new animal models of neurodegenerative diseases in order to highlight their advantages and expand upon their potential. Neurodegenerative diseases have been studied in many different animal models. Studying different types of interventions on these pathologies and taking out tissues from specific areas of the brain, such as hippocampus and cerebral cortex, are examples of the many advantages in using animal models. New animal models in neurodegenerative diseases like Alzheimer’s, diabetes, Parkinson’s, and Huntington’s disease are welcome. The collection will include methods such intracerebroventricular injection and DNA methylation for animal models of a neurodegenerative disease. This Methods Collection aims to contribute to the field of neuroscience with new and advantageous animal models of neurodegenerative diseases.

Articles

The 6-hydroxydopamine Rat Model of Parkinson's Disease
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The 6-hydroxydopamine Rat Model of Parkinson's Disease

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Cited by 29

2021

Abstracts

<p>Locomotor Assessment of 6-OHDA-induced Adult Zebrafish-based Parkinson&rsquo;s Disease Model</p>

Kalavathy Ramasamy*1

1Collaborative Drug Discovery Research (CDDR) Group and Brain Degeneration and Therapeutics Group, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM)

<p>Assessing activities of daily living in an animal model of Alzheimer&rsquo;s disease: the Octodon degus</p>

Robert Deacon1

1IEB, GeN Unit, Faculty of Science, University of Chile

Measuring intestinal motility in a C elegans model of early Parkinson’s disease

Amanda Munoz Juan1,

Anna Laromaine2,

Victor J Yuste3,

Esther Dalfo*4

1Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark; Danish Research Institute of Translational Neuroscience—DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Aarhus University, 8000 Aarhus, Denmark,

2Group of Nanoparticles and Nanocomposites, Institut Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Barcelona, Spain.,

3Department of Biochemistry and Molecular Biology, Institut de Neurociències, Faculty of Medicine, M2, Universitat Autònoma de Barcelona (UAB), Bellaterra Campus, Cerdanyola del Vallés, Barcelona, Spain.,

4Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Institute for Research and Innovation in Life Sciences and Health in Central Catalonia (IRIS-CC), Can Baumann, 08500 Vic, Spain; Department of Biochemistry and Molecular Biology, Institut de Neurociències, Faculty of Medicine, M2, Universitat Autònoma de Barcelona (UAB), Bellaterra Campus, Cerdanyola del Vallés, Barcelona, Spain; Department of Biochemistry and Molecular Biology, Institut de Neurociències, Faculty of Medicine, M2, Universitat Autònoma de Barcelona (UAB), Bellaterra Campus, Cerdanyola del Vallès, Barcelona, Spain; Institute of Neurosciences, Faculty of Medicine, Universitat Autònoma de Barcelona (UAB), Campus UAB, 08193 Cerdanyola del Vallès.

Behavioural Response of Artemia salina Under Hydrogen Peroxide and Aluminium Chloride-Induced Stress

Riddhi Upadhyay 1,

Murugan Sevanan*1

1Division of Biotechnology, Karunya Institute of Technology and Sciences (Deemed to be University), Coimbatore, Tamil Nadu-641114, India