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TOPICAL COLLECTIONS

Current methods in chick embryology

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Masahito Yamagata

Masahito Yamagata

Harvard University, Center for Brain Science, Department of Molecular and Cellular Biology

<p>Dr. Masahito&nbsp;is an associate at the Department of Molecular and Cellular Biology, Center for Brain Science at&nbsp;Harvard University.&nbsp;Dr.&nbsp;&nbsp;obtained his&nbsp;PhD&nbsp;in Chemistry from Nagoya University, Japan, and&nbsp;studied extracellular matrix molecules in chick embryos.&nbsp; During his career, he has been working on chick embryos using cutting-edge molecular techniques since then.&nbsp; After a short stay in the Dr. Masatoshi Takeichi laboratory in Kyoto University, Japan as a postdoctoral fellow, he&nbsp;initiated working on the chick retinotectal system in the Dr. Joshua Sanes laboratory at Washington University School of Medicine, St Louis, MO.&nbsp;From 1994-1998, he worked as an assistant professor at the National Institute of Basic Biology, Okazaki, Japan.&nbsp; After moving to Harvard University, Cambridge, MA in 2004, he also started using the mouse retina. His current research interests include the function and development of neural circuits and cell recognition molecules in the visual system.&nbsp;</p> <p>&nbsp;</p>

Collection Overview

In recent decades, the application of new molecular and cellular techniques in avian embryos has opened up new avenues to understanding various biological questions in birds, including chickens (Gallus gallus). Questions include, how cells grow, migrate, differentiate, and function, and how birds behave. These techniques may also be beneficial to existing industries, such as poultry and medicine. For example, emerging single-cell RNA sequencing and related multimodal molecular approaches have led to the description of new cell types and their states. Electroporation, viral vectors, and ever-improving genome editing methods using CRISPR, have allowed us to inquire into the functions of particular genes and visualize specific cell populations in tissues and animals. Chicken eggs are also essential resources for the production of IgY antibodies and vaccines for infectious diseases. This Methods Collection will focus on new techniques with which to study chicken or other avian embryos.

Articles

<em>In Ovo</em> Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth
6:38

In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth

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Cited by 3

2021

Abstracts

<p>Using the chick embryo brain as a model system for in vivo and ex vivo analyses of human glioblastoma cell behavior.</p>

Deni Galileo*1,

Nikki Pastorino1,

To be determined To be determined1

1Dept. of Biological Sciences, University of Delaware