How Cells Build the Contractile Ring

Contractile rings are built from microfilaments and help separate daughter cells during cytokinesis. This ring forms as the cell cycle moves forward, but the exact timing and coordination with other cell cycle events are still not fully understood.

RhoA, a small GTPase in the Ras superfamily, con...

The final step of the cell cycle that divides a cell into two daughter cells is called cytokinesis. Cytokinesis begins after chromosome separation in mitosis and ends when the cell divides.

The beginning of cytokinesis is marked by the appearance of a crease, called the cleavage furrow. Starting in anaphase, the furrow deepens and spreads...