Experimental Platform

An experimental platform is an integrated set of tools, protocols, materials, and measurement methods designed to investigate a scientific question under controlled conditions. In bioengineering, a platform links engineered biological systems or devices with standardized inputs, controlled environments, and quantitative readouts, allowing researchers to vary selected parameters while monitoring system responses. These platforms support reproducible studies of cell behavior, biomaterials, tissue models, biosensors, and therapeutic strategies. By making experiments more systematic and scalable, they help researchers compare designs, identify governing mechanisms, optimize performance, and translate laboratory findings into biomedical technologies.

Experimental Platform - Related Videos

Research

JoVE Journal - Bioengineering

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis

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Cited by 15 •

2014

Neural-machine interfaces (NMI) have been developed to identify the user's locomotion mode. These NMIs are potentially useful for neural control of powered artificial legs, but have not been fully demonstrated. This paper presented (1) our designed engineering platform for easy implementation and development of neural control for powered lower limb prostheses and (2) an experimental setup and protocol in a laboratory environment to evaluate neurally-controlled artificial legs on patients with...

Research

JoVE Journal - Medicine
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Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation

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Cited by 45 •

2016

Intravenous administration of endotoxin reliably elicits dose-dependent physiological and immunological alterations consistent with several pathological states. This reductionist approach permits the investigation, modeling and experimental modification of systemic inflammation and its downstream effects in man.

Research

JoVE Journal - Neuroscience
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An Experimental Platform to Study the Closed-loop Performance of Brain-machine Interfaces

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Cited by 13 •

2011

We use a closed-loop fly-machine interface to investigate general principles in neuronal control.

Experimental Metastatic Melanoma Mouse Model: A Platform to Study the Metastatic Potential of Melanoma Cells in the Lungs

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2023

In this video, melanoma cells are intravenously injected through the tail vein in the mouse model. The melanoma cells further travel through the circulatory system, adapting to the distant microenvironment and causing metastasis in organs like lungs.

Ultrasonography in Experimental Reproductive Investigations on Rats

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Cited by 6 •

2017

This manuscript describes the utility of ultrasound performed on female rats to design experimental models for reproductive and gynecological investigation. A step-by-step explanation of how to perform ultrasonographic evaluation is shown.

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