Hepatic Vein Cannulation
Hepatic Vein Cannulation - Related Videos
06:00
Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
0 Views •
2025
We present a laparoscopic technique for anatomic S7+S8d resection with right hepatic vein transection, preserving the inferior right hepatic vein and segment S6. Relying on meticulous anatomical landmarks without intraoperative ultrasound, this approach offers a precise and parenchyma-sparing option for dorsally located right-liver tumors, particularly in settings with limited advanced navigation resources.
16:19
Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
0 Views •
Cited by 5 •
2014
Auxiliary liver transplantation provides a temporary support in acute hepatic failure, until regeneration of the failing liver. The heterotopic auxiliary liver transplantation (HALT) with portal vein arterialization (PVA) renders sufficient liver function. We developed an analogous technique in the rat, to examine the influence of the portal vein arterialization on the morphology and function of the graft.
05:30
Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse
0 Views •
Cited by 2 •
2022
The protocol describes a straightforward method of resectioning an intact mouse liver for metabolic studies through portal vein perfusion.
07:06
Isolation and Primary Culture of Rat Hepatic Cells
0 Views •
Cited by 137 •
2012
Primary hepatocytes provide a valuable tool to evaluate biochemical, molecular, and metabolic functions in a physiologically relevant experimental system. We describe a reliable protocol for rat in situ liver perfusion, which consistently generates viable hepatocytes up to 1.0 × 108 cells per preparation with cell viability between 88 ~ 96%.
10:40
Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
0 Views •
Cited by 10 •
2012
An optical system was developed to visualize hepatic microcirculation with FITC-labeled erythrocytes and to measure the partial pressure of oxygen in the microvessels with laser-assisted phosphorimetry. This method can be used to investigate physiological and pathological mechanisms by analyzing microvascular structure, diameter, blood flow velocity, and oxygen tension.
FAQs
Imaging guidance helps track the catheter as it moves through the venous system and confirms that its tip reaches the intended hepatic vein. This positioning is important because measurements, blood samples, and fluid delivery depend on access to the liver’s blood outflow rather than another vascular region. It therefore supports controlled and interpretable experiments.
The hepatic venous outflow provides a direct sampling and measurement point for blood leaving the liver. Access at this location can support blood collection and vascular pressure recording, allowing investigators to examine hepatic circulation and liver function. These measurements also provide physiological context when evaluating engineered systems or therapeutic approaches involving liver transport.
This approach can be used to investigate hepatic circulation, liver function, transport, and drug distribution. The catheter creates an interface for observing vascular pressure, collecting blood, or controlling fluid movement at the liver outflow. In bioengineering studies, those capabilities help connect vascular behavior with device performance, engineered liver models, or treatment strategies.
A typical workflow begins by introducing the catheter into the venous system, advancing it under imaging guidance, and positioning its tip in a hepatic vein. Once access is established, the catheter can support blood sampling, vascular pressure recording, or controlled fluid delivery. The procedure therefore combines guided placement with a defined measurement or delivery objective.
The essential setup includes a catheter, imaging guidance, and a system that supports controlled fluid flow when delivery or flow-based measurements are required. The catheter must remain positioned in the hepatic vein while investigators collect blood or record pressure. These components create a controlled interface between the liver’s vasculature and an external experimental system.
Researchers can apply hepatic vein cannulation when a study requires precise vascular access to evaluate hepatic circulation, liver function, transport, or drug distribution. It also supports testing of liver-on-chip systems, implanted devices, and therapeutic strategies that depend on controlled interaction with the liver’s blood outflow. The resulting access links engineered interventions with measurable hepatic vascular behavior.