Intracortical Electrodes

Intracortical electrodes are small conductive interfaces implanted within the cerebral cortex to record or modulate neural activity, making them important tools in bioengineering and neural prosthetics. Their electrode contacts detect extracellular voltage changes produced by nearby neurons, while controlled electrical currents can stimulate cortical tissue; signal-processing systems then translate recorded activity into digital commands. Microelectrode arrays support studies of cortical function and enable brain-computer interfaces that can control robotic limbs, computer cursors, or other assistive devices. Ongoing research aims to improve signal quality, biocompatibility, long-term stability, and safe integration with neural tissue.

Intracortical Electrodes - Related Videos

Research

JoVE Journal - Behavior

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

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Cited by 21 •

2017

Using two different transcranial magnetic stimulation (TMS) protocols, this manuscript describes how to measure and compare cortical inhibition within the primary motor cortex when adopting different attentional foci.

Implanting an On-Head Electrode System in a Rat Model for Real-Time Seizure Detection

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2025

This video demonstrates the method of implanting an on-head electrode system in an anesthetized rat for real-time seizure detection. The procedure includes placing stimulation and recording electrodes, securing them with dental cement, and connecting them to a head-mounted amplifier.

Education

JoVE Core - Chemistry

Standard Electrode Potentials

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2020

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...

Fabrication of Amperometric Electrodes

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Cited by 8 •

2009

This protocol describes how to generate carbon fiber electrodes. The electrodes are subsequently used to detect catecholamine release from vesicles with carbon fiber amperometry.

Research

JoVE Journal - Cancer Research
Free Sample

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection

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Cited by 1 •

2026

The stereotactic intracranial injection technique enables precise and localized implantation of tumor cells into the mouse cortex, making it a powerful model for studying metastatic colonization of the brain.

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