Nanoprobe Injection

Nanoprobe injection is a technique for introducing nanoscale probes into individual cells or tissues, enabling researchers to examine biological processes with high spatial precision. In a typical procedure, a fine micropipette or needle delivers a controlled volume of nanoprobe suspension across the cell membrane or into a tumor-associated site, where the probes can interact with or report on specific molecular environments. In cancer research, this approach supports intracellular imaging, localized molecular sensing, and studies of how tumor cells respond to their microenvironment or treatment. By linking nanoscale measurements with cellular behavior, nanoprobe injection can improve the resolution of cancer diagnostics and experimental therapies.

Nanoprobe Injection - Related Videos

Research

JoVE EoE - Immunodiagnostics

A Technique to Detect Extrapulmonary Tuberculosis via Superparamagnetic Nanoprobes

0 Views •

2025

This video demonstrates a technique for the detection of extrapulmonary tuberculosis. Superparamagnetic iron oxide (SPIO) nanoprobes, conjugated to Mycobacterium-specific antibodies, are injected into a mouse previously infected with Mycobacterium bovis BCG, labeling the granuloma and providing a better imaging contrast for its detection.

Antibody-Functionalized SERRS Nanoprobe Based Imaging: A Highly Sensitive Raman-imaging Technique to Detect Metastatic Ovarian Cancer In Vivo

0 Views •

2023

This video describes the surface-enhanced resonance Raman scattering technique to detect metastatic ovarian cancer using targeted nanoprobes specific anti-receptor antibodies and non-targeted control nanoprobes. This method helps to determine the relative abundance of the two nanoprobes and differentiate the cancer cells from the visceral background.

Research

JoVE Journal - Chemistry
Free Sample

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

0 Views •

Cited by 5 •

2018

In this work, a protocol for signal enhancement of nanoprobe-based biosensing is presented. The protocol is based on the reduction of chloroauric acid onto the surface of existing nanoprobes that consist of gold, silver, silica or iron-oxide nanoparticles.

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

0 Views •

Cited by 2 •

2010

We present principles of oxygen measurements by phosphorescence quenching and review design of porphyrin-based dendritic nanosensors for oxygen imaging in biological systems.

Label-Free Surface-Enhanced Raman Scattering Bioanalysis Based on Au@Carbon Dot Nanoprobes

0 Views •

Cited by 3 •

2023

In this study, we developed a low-cost surface-enhanced Raman scattering (SERS)-based fingerprint nanoprobe with favorable biocompatibility to show label-free live cell bioimaging and detect two bacterial strains, showing in detail how to get SERS spectra of living cells in a non-destructive method.

View All Results

FAQs

Related Topics