Rotor Patterns

Rotor patterns are organized, rotating electrical activation patterns in excitable tissue, particularly cardiac muscle, that help explain how certain arrhythmias begin and persist. They arise when an electrical wavefront repeatedly travels around a functional or anatomical core, supported by reentry, conduction differences, and variations in tissue refractoriness. In medicine, researchers use electrical mapping and computational models to identify rotor-like activity in conditions such as atrial fibrillation and other rhythm disorders. Characterizing these patterns can improve understanding of arrhythmia maintenance, guide investigation of targeted ablation strategies, and support the development of more precise approaches to cardiac diagnosis and treatment.

Rotor Patterns - Related Videos

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JoVE Journal - Bioengineering
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Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells

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Cited by 17 •

2012

Fluorescence Lifetime Imaging (FLIM) has emerged as a key technique to image the environment and interaction of specific proteins and dyes in living cells. FLIM of fluorescent molecular rotors allows mapping of viscosity in living cells.

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JoVE Journal - Engineering

How to Build a Vacuum Spring-transport Package for Spinning Rotor Gauges

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Cited by 1 •

2016

Here we describe how to build a robust spring-transport mechanism for a spinning rotor gauge. This device securely immobilizes the rotor and keeps it under vacuum during transportation. We also describe packaging that minimizes the risk of damage during transport. Tests show our design works for typical shocks during transport.

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JoVE Journal - Neuroscience
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Cross-Modal Multivariate Pattern Analysis

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Cited by 5 •

2011

Classical multivariate pattern analysis predicts sensory stimuli a subject perceives from neural activity in the corresponding cortices (e.g. visual stimuli from activity in visual cortex). Here, we apply pattern analysis cross-modally and show that sound- and touch-implying visual stimuli can be predicted from activity in auditory and somatosensory cortices, respectively.

A Versatile Method of Patterning Proteins and Cells

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Cited by 10 •

2017

This report describes a simple, easy to perform technique, using low pressure vacuum, to fill microfluidic channels with cells and substrates for biological research.

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