Brain Function Analysis

Brain function analysis is the systematic study of how neural activity and brain systems support behavior, cognition, and physiological regulation. It works by combining measurements such as neural signals, brain imaging, behavioral performance, and responses to controlled tasks to identify relationships between brain activity and function. In neuroscience, these analyses help characterize processes including perception, learning, memory, decision-making, and motor control, while revealing how injury, disease, or development alters neural function. The approach supports basic research, clinical assessment, and evaluation of interventions by linking cellular and network-level mechanisms to observable behavior.

Brain Function Analysis - Related Videos

Research

JoVE Journal - Neuroscience

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Cited by 17 •

2012

We describe a novel approach for simultaneous analysis of brain function and structure using magnetic resonance imaging (MRI). We assess brain structure with high-resolution diffusion-weighted imaging and white-matter fiber tractography. Unlike standard structural MRI, these techniques allow us to directly relate anatomical connectivity to functional properties of brain networks.

Isolation and Functional Analysis of Arteriolar Endothelium of Mouse Brain Parenchyma

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Cited by 2 •

2022

Intensive preparation of intact mouse cerebral endothelial "tubes" from cerebral parenchymal arterioles is illustrated for studying cerebral blood flow regulation. Further, we demonstrate the experimental strengths of this endothelial study model for fluorescence imaging and electrophysiology measurement of key cellular signaling pathways, including changes in intracellular [Ca2+] and membrane potential.

Using Saccadometry with Deep Brain Stimulation to Study Normal and Pathological Brain Function

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Cited by 7 •

2016

This paper describes the use of quantitative measurement of eye movements in conjunction with stimulation of focal areas of the deep brain in order to study physiology, pathophysiology, and the mechanisms of deep brain stimulation.

Research

JoVE Journal - Neuroscience
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Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

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Cited by 17 •

2011

The effect of weightlessness and hypergravity on both hemodynamic and electrophysiological processes in the brain is going to be followed during parabolic flight by EEG and NIRS techniques. A feasibility study of a more complex experiment, which is planned to carry out during medium- and long-term space flight.

Mosaic Analysis of Gene Function in Postnatal Mouse Brain Development by Using Virus-based Cre Recombination

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Cited by 9 •

2011

An in vivo method to test gene function in postnatal brain is described. Recombinant AAVs expressing Cre and/or a fluorescent protein are injected into neonatal mouse brain. Mosaic gene inactivation and sparse neuronal labeling are achieved, allowing rapid analysis of gene function in processes critical to neural circuit development.

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