Gas-propelled Impactor

A gas-propelled impactor is a laboratory device that uses pressurized gas to deliver a controlled mechanical impact, helping researchers model traumatic brain injury and study its neurological consequences. In a typical experiment, compressed gas accelerates a piston or impactor against the skull or exposed dura, producing a defined deformation or force while researchers regulate impact intensity and timing. This approach supports controlled investigations of tissue damage, neuroinflammation, neuronal dysfunction, and behavioral changes in experimental models. By standardizing injury conditions, gas-propelled impactors improve comparisons across studies and help evaluate mechanisms of brain trauma and potential therapeutic interventions.

Gas-propelled Impactor - Related Videos

Education

JoVE Science Education - Engineering

Propeller Characterization: Variations in Pitch, Diameter, and Blade Number on Performance

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2023

Source: Shreyas Narsipur, Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC A propeller is a twisted airfoil, where the angle of the chord changes with respect to the location, along the radial station, as shown in Figure 1. Propellers are widely used in aircraft and watercraft propulsion systems thereby necessitating detailed characterizations of propellers to design high performance vehicles. Figure 1. Chord, thickness, and pitch at a radial station. One of...

Research

JoVE EoE - Neuropathology

Generating a Mouse Model of Traumatic Brain Injury Using an Impactor Device

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2025

This video demonstrates the procedure for inducing traumatic brain injury (TBI) in a mouse model. An anesthetized mouse with an exposed skull is taken to create an opening in the skull, and then a controlled cortical injury is induced using an impact device. The injury damages the brain tissue, causing impaired cognitive function and motor coordination.

Generating a Traumatic Brain Injury Mouse Model Using an Impactor Probe

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2025

This video demonstrates the procedure for inducing an open-skull traumatic brain injury in a mouse by making a midline skull incision, drilling through the skull and removing the bone flap to expose the brain cortex, and applying high pressure to induce trauma. The wound is then sutured to prepare the mouse model for subsequent experiments.

A Contusive Model of Unilateral Cervical Spinal Cord Injury Using the Infinite Horizon Impactor

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Cited by 46 •

2012

A reliable and repeatable way to produce a cervical unilateral spinal cord injury using the Infinite Horizon impactor is described. The method takes advantage of a custom designed frame and clamp to stabilize the spine. The standardized procedure and biomechanical injury parameters result in sufficient and sustained injuries.

Gas Absorber

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2023

Source: Michael G. Benton and Kerry M. Dooley, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Gas absorbers are used to remove contaminants from gas streams. Multiple designs are used to accomplish this objective1. A packed bed column uses gas and liquid streams running counter to each other in a column packed with loose packing materials, such as ceramics, metals, and plastics, or structured packing1. The packed bed uses surface area created by the packing to...

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