Inductie van kleine kolonies in Candida glabraat via Bengaalse rozengemedieerde fotodynamische therapie

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09:06 min.

29 maart 2024

10.3791/66549-v

29 maart 2024

1.5K weergaven

Cai-Ying Yang^*¹^,² , Jia-Horung Hung^*³ , Chi-Jung Wu⁴^,⁵ , Zhao-Xiang Wang¹^,² , Shih-Han Wang⁶ , Hao-Chun Liaw² , I-Huang Lin³ , Chun-Keung Yu¹^,⁶ , Tak-Wah Wong²^,⁷^,⁸

¹Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, ²Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ³Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ⁴National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, ⁵Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ⁶Insititute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, ⁷Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, ⁸Center of Applied Nanomedicine, National Cheng Kung University

^* These authors contributed equally

De betekenis van kleine kolonies in resistentie tegen geneesmiddelen tegen Candida spp. is nog niet volledig onderzocht. Antimicrobiële fotodynamische therapie (aPDT) biedt een veelbelovende strategie tegen resistente schimmelinfecties. Deze studie toont aan dat roos bengaal-gemedieerde aPDT Candida glabrata effectief deactiveert en kleine kolonies induceert, wat een unieke procedure oplevert.

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Chapters in this video

0:00

Introduction

1:46

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4:02

Mitochondrial Function Analysis in Fluconazole‐Induced Petite Colonies of Candida glabrata

5:47

Mitochondrial Function Analysis in Antifungal Photodynamic Therapy Induced Petite Colonies of Candida glabrata