Coronary Sinus Cannulation

Coronary sinus cannulation is a procedure that places a catheter into the coronary sinus, the major venous channel draining blood from the heart muscle, to enable controlled access to cardiac circulation. Typically, clinicians advance the catheter through venous access into the right atrium and guide its tip into the coronary sinus, where secure positioning allows blood sampling, pressure measurement, or infusion. In bioengineering, this approach supports retrograde delivery of cardioplegia, targeted therapeutics, and contrast agents while informing the design of catheters, sensors, and cardiac support systems. Its effectiveness depends on accurate navigation, stable placement, and controlled flow within the coronary venous anatomy.

Coronary Sinus Cannulation - Related Videos

Research

JoVE Journal - Medicine

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

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Cited by 7 •

2017

Surgical correction of ALCAPA is highly recommended, regardless of age or the degree of intercoronary collateralization. This protocol presents a technique for the direct re-implantation of adult-type ALCAPA into the aorta to re-establish the dual-coronary perfusion. Whenever feasible, direct re-implantation is preferred to other surgical correction techniques.

Education

JoVE Science Education - Clinical Skills

Nose, Sinuses, Oral Cavity and Pharynx Exam

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2023

Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA This video provides an overview of sinus, nose, and throat examinations. The demonstration begins with a brief overview of the anatomy of the region. The upper third of the nose is bony, and the bottom two-thirds are cartilaginous. Air entering the nares passes through the nasal vestibules and into the narrow passageway between the nasal septum...

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

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Cited by 51 •

2013

We describe procedures to quantify and characterize atherosclerotic lesions in mouse models using precision sectioning of the aortic sinus and ascending aorta combined with histochemical and immunohistochemical analysis.

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis

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2025

This study presents a protocol for establishing a reproducible, minimally invasive rat model of superior sagittal sinus thrombosis induced by ferric chloride, utilizing a silk-suture method in combination with laser speckle contrast imaging and high-resolution ultrasound for evaluation.

Intraduodenal Cannulation in a Rat Model for Immunopathology Studies

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2025

This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.

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