Organic Loading Rate

Organic loading rate is the amount of biodegradable organic matter applied to a biological treatment system per unit of reactor volume and time, making it a key measure of process demand in bioengineering. It is typically calculated from influent substrate concentration and flow divided by reactor volume, and it influences microbial growth, oxygen consumption, substrate removal, and sludge production. In aerobic and anaerobic wastewater treatment, controlling organic loading rate helps maintain stable microbial communities and effective pollutant conversion. Monitoring this parameter supports reactor design, performance evaluation, process optimization, and prevention of overload conditions that can reduce treatment efficiency.

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Education

JoVE Core - Pharmacokinetics and Pharmacodynamics

Factors Affecting Drug Distribution: Organ Perfusion Rate

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2025

Drug distribution within the body is a complex process influenced by several factors, including perfusion rate, the rate at which the bloodstream transports drugs to tissue. This limitation becomes particularly significant when dealing with highly lipophilic drugs. In such cases, the rate at which the drug can move across membranes is crucial, and if the membrane is highly permeable to the drug, distribution becomes rate-limited by perfusion. Perfusion rate-limited distribution relies on the...

Research

JoVE Journal - Environment
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Temperature Response of Soil Organic Matter Decomposition Rates: Construction and Applications of a Temperature Gradient Block

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2026

We introduce a temperature gradient block and detail its construction and utilization. The block provides 22 discrete temperatures, linearly distributed between a user-defined range from 0 to 90 °C. Data collected from this setup enables testing and developing new theories on the temperature response of soil organic matter decomposition rates.

Reaction Rate

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2020

The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure. The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...

Related Rates

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2026

When two or more physical quantities are linked by a single relationship, a change in one variable necessarily affects the others. This interdependence forms the basis of related rates analysis, which examines how different quantities change with respect to time. A classic physical example is an expanding balloon, where the size of the balloon changes continuously as air is added.For a hot air balloon, the inflated envelope is commonly idealized as a perfect sphere to simplify mathematical...

Measuring Reaction Rates

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2020

Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical field in...

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