Ultrasound Advanced Open Platform
Ultrasound Advanced Open Platform - Related Videos
08:22
Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
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Cited by 16 •
2014
Echocardiography-guided percutaneous intramyocardial injection represents an efficient, reliable, and targetable modality for the delivery of gene transfer agents or cells into the murine heart. Following the steps outlined in this protocol, the operator can quickly become competent in this versatile, minimally invasive technique.
10:02
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
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Cited by 6 •
2015
This protocol describes the application of high-frequency ultrasound (HFUS) for imaging mouse cervical lymph nodes. This technique optimizes visualization and quantification of cervical lymph node morphology, volume and blood flow. Image-guided biopsy of cervical lymph nodes and processing of lymph tissue for histological evaluation is also demonstrated.
10:53
A Novel Application of Musculoskeletal Ultrasound Imaging
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Cited by 14 •
2013
We describe a new ultrasound-based vector tissue Doppler imaging technique to measure muscle contraction velocity, strain and strain rate with sub-millisecond temporal resolution during dynamic activities. This approach provides complementary measurements of dynamic muscle function and could lead to a better understanding of mechanisms underlying musculoskeletal disorders.
09:00
Murine Echocardiography and Ultrasound Imaging
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Cited by 61 •
2010
This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
05:16
An Ultrasound-Guided Vascular Access Procedure in an Anesthetized Pig
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2026
Source:Rui Cerqueira1,2, Liliana Costa1, André Leite-Moreira1, Adelino Leite-Moreira1,2, André Lourenço1, Pedro Mendes-Ferreira11Department of Surgery and Physiology, Faculty of Medicine of the University of Porto.2Department of Cardiothoracic Surgery, Hospital Universitário de São João.The video demonstrates a procedure for obtaining vascular access in an anesthetized pig using ultrasound guidance. After disinfecting the site and administering local anesthesia, an ultrasound probe is used to...
FAQs
Researchers can change three linked stages: transmit sequence design, data acquisition, and image reconstruction. Adjusting one stage can alter how acoustic echoes are sampled or combined, allowing direct evaluation of alternative imaging and therapeutic approaches. This programmability makes the platform useful for testing algorithms rather than relying on a fixed processing pipeline.
Transducer arrays convert electrical signals into acoustic waves and detect returning echoes from tissue or other materials. Beamforming then combines acquired signal information to support image reconstruction. Together, these components connect hardware control with computational analysis, enabling researchers to investigate how transmit settings and signal-processing choices affect the resulting image or measurement.
The key distinction is access to adjustable system parameters. An open platform allows researchers to modify transmit sequences, acquisition behavior, and reconstruction algorithms, so they can evaluate new configurations directly. This flexibility supports rapid prototyping and quantitative validation, whereas a less accessible system would provide fewer opportunities to test customized hardware-software combinations.
Results depend on the relationship between transmitted acoustic signals, acquired echoes, and the reconstruction process. Changes to transmit sequences, data acquisition, or signal processing can therefore influence the reconstructed information. Researchers can examine these effects systematically by comparing configurations and using quantitative validation, helping distinguish genuine tissue or material features from changes introduced by the measurement pipeline.
A study can begin by selecting a transmit sequence and configuring the transducer array, followed by collecting echo data from tissue or another material. Researchers then apply beamforming and signal-processing procedures to reconstruct images or derive measurements. They can modify the configuration, compare results, and quantitatively validate how each choice affects imaging or therapeutic evaluation.
The platform supports tissue characterization, flow measurement, and functional imaging by allowing researchers to adapt acquisition and reconstruction for different measurement goals. It also supports therapeutic ultrasound studies, where programmable control can help evaluate treatment-related approaches. These applications make the system relevant to both biological measurement and the development of ultrasound-based interventions.
Open control allows ultrasound experiments to be integrated with emerging bioengineering approaches, including advanced image guidance and personalized treatment. Researchers can prototype configurations, evaluate quantitative results, and adjust processing or acquisition strategies for the study objective. This connection between programmable measurement and individualized investigation supports development of methods tailored to specific tissues, materials, or therapeutic questions.