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Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
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Ultrasound-guided Transthoracic Intramyocardial Injection in Mice

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice

DOI:
10.3791/51566-v

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08:22 min

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August 05, 2014

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, , , , ,
1Department of Cardiology,Boston Children’s Hospital, 2Harvard Stem Cell Institute,Harvard University

Chapters

  • 00:05Title
  • 02:02Preparation of Ultrasound-guided Intramyocardial Injection
  • 03:31Intramyocardial Injection
  • 06:32Results: Murine Intramyocardial Injection
  • 07:32Conclusion

Summary

Automatic Translation

Automatic Translation

Echocardiography-guided percutaneous intramyocardial injection represents an efficient, reliable, and targetable modality for the delivery of gene transfer agents or cells into the murine heart. Following the steps outlined in this protocol, the operator can quickly become competent in this versatile, minimally invasive technique.

Tags

Keywords: Ultrasound-guidedTransthoracicIntramyocardial InjectionMurine ModelsCardiovascular DiseaseRegenerative TherapyMinimally InvasiveEchocardiographyTargeted DeliveryMyocardium

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