Ventricular Geometry Deformation
Ventricular Geometry Deformation - Related Videos
09:05
Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Cited by 9 •
2016
Speckle tracking echocardiography is an emerging diagnostic imaging technique for the quantitative assessment of global and regional myocardial performance. Standard view echocardiographic motion images are recorded and deformation parameters are subsequently measured by automated continuous frame-by-frame tracking and motion analysis of speckles within the B-mode images of the myocardium.
02:57
Coordination Number and Geometry
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2020
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar. Coordination Number Molecular Geometry Example 2 linear [Ag(NH3)2]+ 3 trigonal planar [Cu(CN)3]2− 4 tetrahedral(d0 or d10), low oxidation...
12:09
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
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Cited by 14 •
2013
A methodology to estimate ventricular fiber orientations from in vivo images of patient heart geometries for personalized modeling is described. Validation of the methodology performed using normal and failing canine hearts demonstrate that that there are no significant differences between estimated and acquired fiber orientations at a clinically observable level.
02:27
Predicting Molecular Geometry
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2020
VSEPR Theory for Determination of Electron Pair Geometries The following procedure uses VSEPR theory to determine the electron pair geometries and the molecular structures: Write the Lewis structure of the molecule or polyatomic ion. Count the number of electron groups (lone pairs and bonds) around the central atom. A single, double, or triple bond counts as one region of electron density. Identify the electron-pair geometry based on the number of electron groups: linear, trigonal planar,...
09:47
A Microfluidic Technique to Probe Cell Deformability
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Cited by 20 •
2014
We demonstrate a microfluidics-based assay to measure the timescale for cells to transit through a sequence of micron-scale constrictions.
FAQs
Loading conditions alter the pressure and volume a ventricle must accommodate, which changes chamber dimensions and wall configuration. The resulting deformation affects how stress and strain are distributed through the myocardial wall. Examining these changes helps bioengineers distinguish responses associated with normal cardiac work from mechanical abnormalities linked to altered ventricular function.
Wall thickness and chamber curvature influence the way mechanical loads are carried through the ventricle. Because these geometric features affect stress and strain distribution, two ventricles experiencing similar pressure or volume changes may deform differently. Including both variables in analysis improves characterization of ventricular mechanics and supports more realistic computational or experimental assessments.
Electrical activation initiates coordinated myocardial contraction, while relaxation supports subsequent filling. This sequence converts electrical activity into changing pressure and volume, producing time-dependent deformation of the ventricular wall and chamber. Studying that relationship allows bioengineers to connect cardiac activation with mechanical output rather than evaluating geometry as an isolated structural measurement.
Researchers can quantify deformation through medical imaging, experimental measurements, or computational models. These approaches characterize changes in ventricular shape, dimensions, and wall configuration under different functional or loading conditions. Combining the resulting mechanical information with pressure and volume changes can support evaluation of cardiac function and comparison of disease-related or remodeled ventricular states.
Deformation analysis reveals how changes in ventricular shape and wall configuration modify stress and strain distribution. Those measurements can characterize remodeling and identify mechanical abnormalities associated with disease. In bioengineering research, the findings provide a mechanical basis for evaluating altered cardiac function and for comparing ventricular behavior across different structural or loading conditions.
Ventricular deformation analysis informs the design of ventricular assist devices, tissue-engineered constructs, and patient-specific interventions. By describing how geometry, wall properties, and loading affect mechanical behavior, these analyses provide criteria for matching engineered designs to ventricular function. Computational and measurement-based results can therefore connect cardiac mechanics with device development and individualized treatment planning.