Prequalification Of Medicines
Prequalification Of Medicines - Related Videos
08:07
Preparation of Herbal Medicine: Er-Xian Decoction and Er-Xian-containing Serum for In Vivo and In Vitro Experiments
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Cited by 6 •
2017
Here, we present the preparation of an er-xian decoction (EXD) in four steps—soaking, decoction, filtration, and concentration—and demonstrate the administration of a prepared EXD-containing serum to rats. These methods are applicable to the in vivo and in vitro study of herbal decoctions such as traditional Chinese medicines.
06:14
Automating Tumor Implantation in Zebrafish Larvae for Cancer Research and Medicine
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2025
Here, we present a detailed protocol for automated tumor xenograft implantation into zebrafish larvae using a state-of-the-art robotic injection system. Furthermore, we present injection videos and validation data demonstrating the system's successful performance.
01:29
Microorganisms in Medicine and Therapeutics
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2026
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
16:19
Localized RNAi and Ectopic Gene Expression in the Medicinal Leech
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Cited by 5 •
2008
In this video, we show a procedure for an accurate biolistic delivery of reagents into live tissue with a novel miniature gene gun. We are knocking down the expression of the axon guidance molecule Netrin in leech embryos by delivering molecules of dsRNA into the ventral body wall and ganglia of single segments.
04:24
Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease
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2025
This protocol describes the specific process and efficacy of acupoint application in treating fatigue symptoms associated with chronic obstructive pulmonary disease.
FAQs
Dossier review provides the documentary basis for judging whether a pharmaceutical product aligns with internationally recognized standards. It is considered together with manufacturing-site evaluation, sample testing, and clinical evidence rather than treated as an isolated step. This combined assessment helps create a more complete picture of product reliability for procurement and public health decisions.
Manufacturing-site evaluation examines the setting in which a product is produced and supports assessment of whether manufacturing standards are applied consistently. This matters because reliable supply depends not only on the product itself but also on the processes used to make it. The resulting information can strengthen confidence in medicines selected for national programs and global health initiatives.
Testing product samples adds an assessment based on the medicine itself to the documentary and site-based parts of the process. When combined with dossier review and manufacturing evaluation, sample testing helps support a broader judgment about quality. This evidence is useful when agencies and programs need greater confidence in products entering public-sector procurement channels.
Clinical evidence addresses whether a medicine has an appropriate basis for evaluating safety and efficacy, two central considerations in clinical practice. Its review complements quality-focused activities such as dossier assessment, site evaluation, and sample testing. Together, these elements help public health programs select treatments with evidence supporting their intended clinical use.
Continued monitoring extends oversight beyond the initial assessment and recognizes that confidence in a medicine must be maintained over time. It provides a way to keep attention on product quality, safety, and efficacy after approval. For procurement agencies and national programs, ongoing monitoring supports more dependable medicine supply and sustained public health confidence.
Procurement agencies and national programs can use prequalification findings when selecting medicines, particularly where regulatory resources are limited. The process offers a structured basis for identifying products that have undergone dossier review, site evaluation, sample testing, and clinical evidence assessment. This can support access to essential treatments and supply through global health initiatives.