Breast Tissue Orientation

Breast tissue orientation is the anatomical description of how the breast, including its skin, fat, glandular tissue, ducts, vessels, and supporting structures, is arranged in relation to the chest wall and surface landmarks. This organization follows predictable directions and tissue planes, while the lobules and ducts extend from the nipple toward the peripheral breast and axillary region. Understanding these relationships helps clinicians interpret physical examinations, mammograms, ultrasound, magnetic resonance images, and biopsy findings. Accurate orientation also supports standardized lesion localization, surgical planning, communication among healthcare professionals, and assessment of how disease affects normal breast anatomy.

Breast Tissue Orientation - Related Videos

Research

JoVE Journal - Medicine

Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization

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Cited by 4 •

2016

Here we present a protocol to detect miRNA expression in breast cancer patient samples using miRNA in situ hybridization.

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

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Cited by 5 •

2021

This protocol describes the construction of an in vitro microphysiological system for studying breast cancer using primary human breast tissue with off the shelf materials.

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

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Cited by 13 •

2013

We demonstrate methods for the detection of architectural distortion in prior mammograms. Oriented structures are analyzed using Gabor filters and phase portraits to detect sites of radiating tissue patterns. Each site is characterized and classified using measures to represent spiculating patterns. The methods should assist in the detection of breast cancer.

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

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2025

This prospective study evaluated the implementation of a novel, single-port, robotic platform in oncoplastic breast-conserving surgery for malignant lesions. The primary endpoint focused on technical success, defined as the achievement of tumor-free resection margins confirmed by intraoperative frozen-section histopathology, with secondary assessment of aesthetic outcomes and life quality score of patients.

Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines

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Cited by 116 •

2015

Floating mammosphere assays can investigate the subset of stem-like breast cancer cells that survive in suspension conditions and show enhanced tumorigenesis when implanted into mice. This protocol provides a convenient in vitro measure of sphere-forming ability, a proxy for in vivo tumorigenesis, while facilitating analysis of the stem-associated transcriptional landscape.

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