Cyanoacrylate Sealing

Cyanoacrylate sealing is a method of closing or protecting tissue surfaces with a fast-setting synthetic adhesive, offering a suture-free approach to selected wound-management procedures. When the liquid adhesive contacts moisture on the skin or tissue, cyanoacrylate monomers rapidly polymerize into a flexible film that bonds adjacent surfaces and forms a barrier against external contamination. In medicine, this technique can approximate superficial skin edges, reinforce incisions, control minor bleeding, and seal selected leaks or puncture sites. Its rapid application and minimal tissue manipulation support efficient care, while appropriate formulation and careful patient selection help limit irritation and ensure reliable healing.

Cyanoacrylate Sealing - Related Videos

Research

JoVE Journal - Chemistry

A Protocol for the Production of Gliadin-cyanoacrylate Nanoparticles for Hydrophilic Coating

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2016

This article presents a protocol for the production of protein-based nanoparticles that changes the hydrophobic surface to hydrophilic. The produced nanoparticle is an assembly of gliadin-cyanoacrylate diblock copolymers. Spray coating with the produced nanoparticle changes the surface of target material to a hydrophilic surface.

Optimized Sealing Process and Real-Time Monitoring of Glass-to-Metal Seal Structures

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Cited by 7 •

2019

Key procedures to optimize the sealing process and achieve real-time monitoring of the metal-to-glass seal (MTGS) structure are described in detail. The embedded fiber Bragg grating (FBG) sensor is designed to achieve online monitoring of temperature and high-level residual stress in the MTGS with simultaneous environmental pressure monitoring.

Research

JoVE Journal - Medicine
Free Sample

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

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Cited by 8 •

2010

The C-seal is a biofragmentable drain protecting the stapled colorectal anastomosis. In this video, details of the manufacturing, deployment and use are shown.

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

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2026

A novel sealing protocol to produce water-tight silicone-based seals for membranes of Polydimethylsiloxane (PDMS) chip devices. Intended for labs setting-up chip models and small-scale chip platform development. We demonstrate the protocol using plastic and native tissue membranes. This procedure only requires PDMS, toluene, mold, membrane, and a vacuum chamber.

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

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2025

This protocol presents the management for gastroesophageal varices (GEVs) with endoscopic injection sclerotherapy assisted by cyanoacrylate and clips (CISC), which can improve the effectiveness of sclerotherapy and reduce complications.

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