Lung Parenchyma Segmentation

Lung parenchyma segmentation is the process of delineating functional lung tissue from surrounding structures in medical images, especially computed tomography scans, to support quantitative analysis and diagnosis. It typically analyzes voxel intensity, anatomical boundaries, and spatial relationships to separate aerated lung regions from the chest wall, mediastinum, major airways, and abnormal tissue, using methods such as thresholding, region growing, or deep-learning models. In medicine, accurate segmentation enables measurement of lung volume, density, lesion burden, and disease distribution. These measurements support the assessment of conditions such as emphysema, pulmonary fibrosis, and infection, while also improving imaging-based research and treatment planning.

Lung Parenchyma Segmentation - Related Videos

Research

JoVE Journal - Biology

Laparoscopic Left Liver Sectoriectomy of Caroli's Disease Limited to Segment II and III

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Cited by 5 •

2009

This video presents a case of laparoscopic left liver sectoriectomy perfomed in a 53 year old man suffering from Caroli's disease limited to segment II and III of the liver.

Research

JoVE Journal - Biology
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Micro-Mechanical Characterization of Lung Tissue Using Atomic Force Microscopy

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Cited by 127 •

2011

The stiffness of the extracellular matrix strongly influences multiple behaviors of adherent cells. Matrix stiffness varies spatially throughout a tissue, and undergoes modification in various disease conditions. Here we develop methods to characterize spatial variations in stiffness in normal and fibrotic mouse lung tissue using atomic force microscopy microindentation.

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

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2026

Robotic-assisted pneumonectomy is safe and effective in the management of Vanishing Lung Syndrome, with reduced morbidity and faster recovery times.

A Simple Method of Mouse Lung Intubation

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Cited by 50 •

2013

This paper describes a striaghforward and efficient method of intubating mice for pulmonary function measurements or pulmonary instillation, that allows the mice to recover and be studied at later times. The procedure involves an inexpensive fiberoptic light source that directly illuminates the trachea.

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

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Cited by 16 •

2012

Simple and reproducible procedures are described for making three structurally distinct collagen assemblies from a common commercially available Type I collagen monomer. Native type, fibrous long spacing or segmental long spacing collagen can be constructed by varying the conditions to which the 300 nm long and 1.4 nm diameter monomer building block is exposed.

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