Percutaneous Closure

Percutaneous closure is a minimally invasive medical technique that seals an opening, defect, or access site through a catheter inserted through the skin, reducing the need for open surgery. Depending on the clinical target, clinicians guide a closure device or delivery system to the site using imaging, where mechanical expansion, suturing, or deployment of occlusive material blocks blood flow or reinforces tissue. The approach is used in interventional cardiology and vascular medicine to close selected septal defects, patent vessels, or vascular access sites. Its potential benefits include smaller incisions, reduced tissue trauma, shorter recovery, and more precise treatment.

Percutaneous Closure - Related Videos

Education

JoVE Science Education - Clinical Skills

Percutaneous Cricothyrotomy

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA A surgical airway procedure is indicated when other forms of endotracheal intubation have failed and ventilation is worsening or not possible. This is the feared "can't intubate, can't ventilate" scenario, and in the emergency setting, cricothyrotomy is the surgical procedure of choice. Cricothyrotomy is preferred over tracheotomy because of the lower risk of complications, the predictable anatomy...

Research

JoVE Journal - Neuroscience
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Neural Tube Closure in Mouse Whole Embryo Culture

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Cited by 22 •

2011

A method allowing for direct pharmacological manipulation of mouse embryos during neurulation that bypasses maternal metabolism is described. The technique can be adapted to study different aspects of neurulation by varying the time point and pharmacological agent.

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

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Cited by 30 •

2015

We present a protocol to assess changes in neuromuscular function. Percutaneous electrical nerve stimulation is a non-invasive method that evokes muscular responses. Electrophysiological and mechanical properties of these responses permit the evaluation of neuromuscular function from brain to muscle (supra-spinal, spinal and peripheral levels).

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

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Cited by 12 •

2016

In this manuscript, we describe percutaneous isolated hepatic perfusion with simultaneous chemofiltration as treatment for unresectable liver metastases. This procedure is performed under general anaesthesia in the angiosuite by an experienced team, consisting of an interventional radiologist, a clinical perfusionist and anaesthesiologist.

Research

JoVE Journal - Medicine
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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

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Cited by 49 •

2012

The accompanying video describes a procedure for percutaneous placement of the WATCHMAN Left Atrial Appendage (LAA) Device. The WATCHMAN is a nitinol device designed to be permanently implanted at, or slightly distal to, the opening of the left atrial appendage (LAA) to trap blood clots before they exit the LAA, preventing thromboembolic stroke.

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